1. Catuneanu A, Paylor JW, Winship I, Colbourne F, Kerr BJ. Sex differences in central nervous system plasticity and pain in experimental autoimmune encephalomyelitis. Pain. 2019; 160(5): 1037-49. [DOI:10.1097/j.pain.0000000000001483]

2. Sandkühler J. Understanding LTP in pain pathways. Molecular pain. 2007; 3: 9. [DOI:10.1186/1744-8069-3-9]

3. Kuner R. Spinal excitatory mechanisms of pathological pain. Pain. 2015; 156: S11-S7. [DOI:10.1097/j.pain.0000000000000118]

4. Tan AM. Dendritic spine dysgenesis in neuropathic pain. Progress in molecular biology and translational science. 2015; 131: 385-408. [DOI:10.1016/bs.pmbts.2014.12.001]

5. Bassi MS, Mori F, Buttari F, Marfia GA, Sancesario A, Centonze D, et al. Neurophysiology of synaptic functioning in multiple sclerosis. Clinical Neurophysiology. 2017; 128(7): 1148-57. [DOI:10.1016/j.clinph.2017.04.006]

6. West SJ, Bannister K, Dickenson AH, Bennett DL. Circuitry and plasticity of the dorsal horn--toward a better understanding of neuropathic pain. Neuroscience. 2015; 300: 254-75. [DOI:10.1016/j.neuroscience.2015.05.020]

7. Kuner R. The plastic spinal cord: functional and structural plasticity in the transition from acute to chronic pain. e-Neuroforum. 2017; 23(3): 137-43. [DOI:10.1515/nf-2017-A016]

8. Lu J, Luo C, Bali KK, Xie R-G, Mains RE, Eipper BA, et al. A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses. Nat Commun. 2015; 6: 6820. [DOI:10.1038/ncomms7820]

9. Rangachari M, Kuchroo VK. Using EAE to better understand principles of immune function and autoimmune pathology. J Autoimmun. 2013; 45: 31-9. [DOI:10.1016/j.jaut.2013.06.008]

10. Olechowski CJ, Truong JJ, Kerr BJ. Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE). Pain. 2009; 141(1-2): 156-64. [DOI:10.1016/j.pain.2008.11.002]

11. Learmonth YC, Motl RW. Exercise Training for Multiple Sclerosis: A Narrative Review of History, Benefits, Safety, Guidelines, and Promotion. International Journal of Environmental Research and Public Health. 2021; 18(24): 13245. [DOI:10.3390/ijerph182413245]

12. Rostami Z, Ghasemi S, Farzadmanesh H, Safari M, Ghanbari A. Sex Difference in Trigeminal Neuropathic Pain Response to Exercise: Role of Oxidative Stress. Pain Research and Management. 2020; 2020: 3939757. [DOI:10.1155/2020/3939757]

13. Benson C, Paylor JW, Tenorio G, Winship I, Baker G, Kerr BJ. Voluntary wheel running delays disease onset and reduces pain hypersensitivity in early experimental autoimmune encephalomyelitis (EAE). Experimental neurology. 2015; 271: 279-90. [DOI:10.1016/j.expneurol.2015.05.017]

14. Chiang SS, Lee CL, Liu HC, Wang JS, Lee IT, Song YM, et al. Physical activity and albuminuria were associated with painful diabetic polyneuropathy in type 2 diabetes in an ethnic Chinese population. Clinica chimica acta; international journal of clinical chemistry. 2016; 462: 55-9. [DOI:10.1016/j.cca.2016.08.022]

15. Silva BA, Ferrari CC. Environmental enrichment as a promising strategy for aiding multiple sclerosis treatment. Neural Regen Res. 2020; 15(9): 1660-1. [DOI:10.4103/1673-5374.276334]

16. Rodrigues DH, Leles BP, Costa VV, Miranda AS, Cisalpino D, Gomes DA, et al. IL-1β Is Involved with the Generation of Pain in Experimental Autoimmune Encephalomyelitis. Molecular neurobiology. 2016; 53(9): 6540-7. [DOI:10.1007/s12035-015-9552-0]

17. Zorzella-Pezavento SF, Chiuso-Minicucci F, França TG, Ishikawa LL, da Rosa LC, Marques C, et al. Persistent inflammation in the CNS during chronic EAE despite local absence of IL-17 production. Mediators Inflamm. 2013; 2013: 519627. [DOI:10.1155/2013/519627]

18. Segal JP, Bannerman CA, Silva JR, Haird CM, Baharnoori M, Gilron I, et al. Chronic mechanical hypersensitivity in experimental autoimmune encephalomyelitis is regulated by disease severity and neuroinflammation. Brain, behavior, and immunity. 2020; 89: 314-25. [DOI:10.1016/j.bbi.2020.07.010]

19. Shahidi SH, Kordi MR, Rajabi H, Malm C, Shah F, Quchan ASK. Exercise modulates the levels of growth inhibitor genes before and after multiple sclerosis. J Neuroimmunol. 2020; 341: 577172. [DOI:10.1016/j.jneuroim.2020.577172]

20. Ball NJ, Mercado E, Orduña I. Enriched Environments as a Potential Treatment for Developmental Disorders: A Critical Assessment. Frontiers in Psychology. 2019; 10. [DOI:10.3389/fpsyg.2019.00466]

21. Fournier AP, Baudron E, Wagnon I, Aubert P, Vivien D, Neunlist M, et al. Environmental enrichment alleviates the deleterious effects of stress in experimental autoimmune encephalomyelitis. Multiple Sclerosis Journal-Experimental, Translational and Clinical. 2020; 6(4): 2055217320959806. [DOI:10.1177/2055217320959806]

22. Li Z, Wang Y, Zhao J, Zhang H. Dieckol attenuates the nociception and inflammatory responses in different nociceptive and inflammatory induced mice model. Saudi Journal of Biological Sciences. 2021; 28(9): 4891-9. [DOI:10.1016/j.sjbs.2021.06.021]

23. Saffar Kohneh Quchan AH, Kordi MR, Namdari H, Shabkhiz F. Voluntary wheel running stimulates the expression of Nrf-2 and interleukin-10 but suppresses interleukin-17 in experimental autoimmune encephalomyelitis. Neuroscience Letters. 2020; 738: 135382. [DOI:10.1016/j.neulet.2020.135382]

24. Tan AM, Chang Y-W, Zhao P, Hains BC, Waxman SG. Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury. Experimental Neurology. 2011; 232(2): 222-33. [DOI:10.1016/j.expneurol.2011.08.028]

25. Tan AM, Samad OA, Fischer TZ, Zhao P, Persson A-K, Waxman SG. Maladaptive Dendritic Spine Remodeling Contributes to Diabetic Neuropathic Pain. The Journal of Neuroscience. 2012; 32(20): 6795. [DOI:10.1523/JNEUROSCI.1017-12.2012]

26. Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, et al. Neuropathic pain memory is maintained by rac1-regulated dendritic spine remodeling after spinal cord injury. Journal of Neuroscience. 2008; 28(49): 13173-83. [DOI:10.1523/JNEUROSCI.3142-08.2008]

27. Benson C, Paylor JW, Tenorio G, Winship I, Baker G, Kerr BJ. Voluntary wheel running delays disease onset and reduces pain hypersensitivity in early experimental autoimmune encephalomyelitis (EAE). Experimental neurology. 2015; 271: 279-90. [DOI:10.1016/j.expneurol.2015.05.017]

28. Honarmandnasab Y, Kordi MR, Gaeini AA. Effect of Voluntary Training after the Induction of Experimental Autoimmune Encephalomyelitis on Some Myelin-Producing Proteins in Female C57BL/6 Mice. The Journal of Shahid Sadoughi University of Medical Sciences. 2021; 28(12): 3، 300-12. [DOI:10.18502/ssu.v28i12.5777]

29. Einstein O, Katz A, Ben-Hur T. Physical exercise therapy for autoimmune neuroinflammation: Application of knowledge from animal models to patient care. Autoimmunity Reviews. 2022; 21(4): 103033. [DOI:10.1016/j.autrev.2022.103033]

30. Sun X, Li X, Zhou Y, Wang Y, Liu X. Up-regulating TIPE2 alleviates inflammatory pain by suppressing microglial activation-mediated inflammatory response via inhibiting Rac1/NF-κB pathway. Experimental cell research. 2021; 404(1): 112631. [DOI:10.1016/j.yexcr.2021.112631]

31. Tai LW, Yeung SC, Cheung CW. Enriched Environment and Effects on Neuropathic Pain: Experimental Findings and Mechanisms. Pain practice : the official journal of World Institute of Pain. 2018; 18(8): 1068-82. [DOI:10.1111/papr.12706]