:: Volume 5 - The Spring Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2017, 5 - The Spring Supplement of Shefaye Khatam 2 -: 28-28 Back to browse issues page
O 28: Autoimmune Myositis: General Aspects of Pathophysiology, Symptoms and Therapeutic Options
Sven G Meuth *
University Hospital Münster, Neurology Clinic and Institute of Translational Neurology, Albert-Schweitzer-Campus 1, 48149 Münster, Germany , sven.meuth@ukmuenster.de
Abstract:   (3302 Views)

Idiopathic inflammatory myopathies are a heterogeneous group of muscle disorders characterized by chronic muscle inflammation and progressive muscle weakness. Polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM) are the three major subsets based on distinct clinical and histopathological features. Since the pathogenesis remains unclear, therapeutic approaches actually comprise unspecific immunosuppressive strategies with limited success and frequent side effects. Therefore, a deeper understanding of the underlying pathophysiological mechanisms is critically required to develop targeted therapies.

Keywords: Autoimmune Myositis, Chronic Muscle, Strategies
Full-Text [PDF 206 kb]   (732 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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