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Back to browse issues page Shefaye Khatam 2017, 5 - The Supplement of Shefaye Khatam 2: 31-31
O 31: HTLV-1 and Inflammation
Fariba Zemorshedi *
Mashhad University of Medical Sciences, Mashhad, Iran , fz6482@yahoo.com
Abstract:   (46 Views)

Human T-lymphotrophic virus type 1 (HTLV-1) is a retrovirus that is thought to infect approximately 10-20 million people worldwide. The majority of infected individuals remain asymptomatic carriers lifelong. HTLV-1 is thought to cause both local and systemic inflammatory diseases. The most common inflammatory condition associated with HTLV-1 is HTLV-1 associated myelopathy/Tropical spastic paraparesis (HAM/TSP), which occur in 0.25% to 5% of infected individuals. Migration of HTLV-1 infected lymphocytes from periphery into CNS induce a strong immune response and subsequent development of HAM/TSP, which characterized by progressive spastic paraparesis, bladder dysfunction and mild sensory disturbance. HTLV-1 is also associated with other inflammatory conditions such as myositis, uveitis, dermatitis, Alveolitis/bronchiectasis, arthritis and nephritis. 

Keywords: Inflammation, HTLV, CNS
Full-Text [PDF 199 kb]   (18 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience



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Zemorshedi F. O 31: HTLV-1 and Inflammation. Shefaye Khatam. 2017; 5 (S2) :31-31
URL: http://shefayekhatam.ir/article-1-1185-en.html
Back to browse issues page Volume 5 - The Supplement of Shefaye Khatam 2
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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