:: دوره 6، شماره 4 - ( پاییز - 1397 ) ::
دوره 6 شماره 4 صفحات 61-74 برگشت به فهرست نسخه ها
نوروترانسمیترها نقشی کلیدی در نورون‌زایی بالغین ایفاء می‌کنند
وحید حاج علی، حمید رضا مرادی، سجاد سحاب نگاه*
الف. گروه علوم اعصاب، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران ب. مرکز تحقیقات علوم اعصاب شفا، بیمارستان خاتم‌الانبیاء، تهران، ایران ، sahabnegahs@mums.ac.i
چکیده:   (764 مشاهده)

مقدمه: نورون‌های جدید به صورت دائم در مناطق خاصی از مغز بزرگسالان تولید می‌شوند و به صورت عملکردی به شبکه‌های نورونی متصل می‌شوند. سلول‌های بنیادی عصبی در محیط‌های اختصاصی در مغز کنام سلول‌های بنیادی نامیده می‌شوند. نشان داده شده است که نوروترانسمیترها اجزای حیاتی سیگنال‌های کنام را فراهم می‌کنند و از چند جنبه مختلف نورون‌زایی را تحریک می‌کنند. ثابت شده است که تغییر در سیگنال‌های نوروترانسمیتر ممکن است بر روی نورون‌زایی بزرگسالان تأثیر بگذارد. برای مشخص کردن اینکه چگونه مسیرهای پیام‌دهی نوروترانسمیترها، نورون‌زایی را کنترل می‌کنند، کارهای بیشتری لازم است. نتیجه‌گیری: در این مقاله مروری ما در مورد اینکه چگونه پیام‌دهی نوروترانسمیتر تکامل نورون‌های جدید کاربردی را تنظیم می‌کند، بحث می‌کنیم. ما همچنین نقش بالقوه نوروترانسمیترها برای سلول درمانی را بررسی می‌کنیم.

واژه‌های کلیدی: نورون‌زایی، عوامل نوروترانسمیتر، درمان بر پایه سلول و بافت
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نوع مطالعه: مروری | موضوع مقاله: تحقیقات پایه در علوم اعصاب
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دوره 6، شماره 4 - ( پاییز - 1397 ) برگشت به فهرست نسخه ها