:: دوره 8، شماره 2 - ( بهار 1399 ) ::
دوره 8 شماره 2 صفحات 106-93 برگشت به فهرست نسخه ها
اختلال عملکرد سیستم ایمنی ناشی از استرس: تاثیر فرایندهای درون فردی و بین فردی
علی سپهری نژاد ، جواد مومنی ، علی گرجی ، سجاد سحاب نگاه*
الف. مرکز تحقیقات علوم اعصاب، دانشگاه علوم پزشکی مشهد، مشهد، ایران. ب. مرکز تحقیقات علوم اعصاب شفا، بیمارستان خاتم‌الانبیاء، تهران، ایران ، sahabnegahs@mums.ac.ir
چکیده:   (5233 مشاهده)
مقدمه: محققین سایکونوروایمونولوژی با تمرکز بر تحقیقات پایه و بالینی به دنبال این هستند که چگونه عوامل استرس‌زا و احساسات منفی آن‌ها می‌توانند بر شرایط فیزیولوژی و سلامتی اثر بگذارند. مطالعات بالینی نشان می‌دهند که سیستم عصبی مرکزی با سیستم اندوکرین و ایمنی ارتباطی دو طرفه دارد. اختلال سیستم ایمنی ناشی از استرس توسط پاسخ‌های ایمنی سلولی و هومورال رخ می‌دهد. علاوه بر این استرس مزمن با القای تولید سایتوکاین‌های پیش التهابی از قبیل اینترلوکین -6 می‌تواند منجر به افزایش انواع بیماری‌های مزمن شود. نتیجه‌گیری:‌ با توجه به پیامدهای سلامتی پس از استرس، به نظر می‌رسد بهبود دانش ما در روش‌های پیچیده اثرات استرس بر عملکرد ایمنی بدن و همچنین عوامل روانشناسی که ممکن است اثرات استرس بر پاسخ‌های ایمنی را مختل یا بهبود بخشد، ضروری باشد. هدف از این مطالعه، مروری بر یافته‌های جدید در مورد تأثیرات استرس بر سیستم ایمنی و عوامل روانشناسی است که ممکن است این اثر را تنظیم کند.
واژه‌های کلیدی: سیستم ایمنی، سایکونوروایمونولوژی، سلامتی
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نوع مطالعه: مروری | موضوع مقاله: تحقیقات پایه در علوم اعصاب
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دوره 8، شماره 2 - ( بهار 1399 ) برگشت به فهرست نسخه ها