[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 1, Issue 4 (Autumn - 2013) ::
Shefaye Khatam 2013, 1(4): 34-41 Back to browse issues page
Optogenetics: Controlling the Function of Neural Cells with Light and its Applications
Mohammad Javad Eslamizade *
a. Shefa Neuroscience Research Center, Tehran, Iran. b. Laboratory of Intracellular Recording and Patch Clamping in Neurodegenerative Diseases, Department of Physiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , eslamizademj@gmail.com
Abstract:   (9893 Views)
Introduction: Manipulating the function of neural cells via electrophysiology and pharmacological agents in neuroscience research have long been interesting in unraveling the function of neural circuits, behavior, and attributed disorders. The power of electrophysiology and pharmacologic methods in the manipulation of neural cells varies and therefore researchers have been attempting to enhance their knowledge in this field in recent two decades. Optogenetics has the advantage to take under control both the temporal and spatial resolution in manipulating desired neural cells. In optogenetics, control over the function of neural cells is possible through shining the light onto the cells that bear light sensitive molecules. Conclusion: Optogenetics come to help the researchers to know how the neural cells, circuits, and systems work and there is an attempt to move toward the treatment of nervous system disorders by this technology. In this article, I reviewed optogenetics and its potential clinical applications.
Keywords: Electrophysiology, Optogenetics, Opsins
Full-Text [PDF 2727 kb]   (2248 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Neurophysiopathology

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Eslamizade M J. Optogenetics: Controlling the Function of Neural Cells with Light and its Applications. Shefaye Khatam. 2013; 1 (4) :34-41
URL: http://shefayekhatam.ir/article-1-52-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 4 (Autumn - 2013) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4419