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:: Volume 1, Issue 4 (Autumn - 2013) ::
Shefaye Khatam 2013, 1(4): 42-49 Back to browse issues page
The Role of TRPV1 Receptors in the Brain Function
Fatemeh Saffarzadeh , Mahmoud Reza Hadjighassem *
Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. , mahmoudreza@hotmail.com
Abstract:   (11745 Views)
Introduction: Transient receptor potential vanilloid 1 (TRPV1) belongs to a family of ligand gated ion channels. This non-selective cation channel is permeable to Na+, K+ and highly to Ca2+ ions. It acts as a trigger for Ca2+ mediated cell signaling. Although this channel has been previously found highly expressed in dorsal root ganglion, there is a line of evidence indicating the remarkable expression of TRPV1 channels in other parts of the central nervous system. Conclusion: There is evidence to suggest that TRPV1 channels in the brain contribute in many basic neuronal functions, including neurotransmitter release and synaptic plasticity.
Keywords: TRPV1 receptor, Synaptic Transmission, Neuronal Plasticity
Full-Text [PDF 2219 kb]   (2766 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Neurophysiopathology

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Saffarzadeh F, Hadjighassem M R. The Role of TRPV1 Receptors in the Brain Function. Shefaye Khatam 2013; 1 (4) :42-49
URL: http://shefayekhatam.ir/article-1-53-en.html
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 4 (Autumn - 2013) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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