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Shefaye Khatam 2015, 3 - The Autumn Supplement of Shefaye Khatam 3 -: 27-27 Back to browse issues page
O27: The Role of Hydrogels and Cell Based Therapies in Regeneration of Spinal Cord Injury
Hadi Aligholi *, Mohammad Torabi-Nami, Bijan Zare
a. Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran b. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran , aligholihadi@gmail.com
Abstract:   (1581 Views)

Spinal cord injury (SCI) is one of the devastating conditions leading to functional and neurological deficits following road traffic accidents. To date, there is no definite treatment for repairing damaged spinal cord tissue. In this regard, cell therapy opens a new window in front of scientists by using different cells such as mesenchymal stem cells, olfactory ensheathing cells, Schwann cells, neural stem cells and induced pluripotent stem cells. But, cell therapy faces some problems related to cell survival, migration and differentiation. Based on the results of recent studies, supporting the transplanted cells with a proper scaffold can be helpful. Among several scaffolds, hydrogels are outstanding one with several beneficial properties for neural tissue engineering. The future of SCI regeneration is probably linked to combinatorial approaches in which both cells and scaffolds play its significant roles.
 

Keywords: Spinal Cord Injury, Road Traffic Accident, Cell Therapy, Tissue Engineering
Full-Text [PDF 170 kb]   (359 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Aligholi H, Torabi-Nami M, Zare B. O27: The Role of Hydrogels and Cell Based Therapies in Regeneration of Spinal Cord Injury. Shefaye Khatam. 2015; 3 (S3) :27-27
URL: http://shefayekhatam.ir/article-1-789-en.html


Volume 3 - The Autumn Supplement of Shefaye Khatam 3 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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