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:: Volume 2, Issue 2 (Spring - 2014) ::
Shefaye Khatam 2014, 2(2): 81-88 Back to browse issues page
Cellular and Molecular Pathways of Learning and Memory
Tahereh Ghadiri , Mostafa Modarres Mousavi , Fatemeh Alipour , Shahin Mohammad Sadeghi *
Department of Plastic and Reconstructive Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. , drshmsadeghi@gmail.com
Abstract:   (4505 Views)

Introduction: Memory is ability to acquisition, maintenance and retrieval of information, which is classified through different ways. Complex mechanisms play a role in learning and memory that ultimately leads to biochemical, morphological and physiological changes at the level of synaptic and neural networks. The basic mechanisms involved in the formation and stabilization of memory are synaptic facilitation, long term potentiation and long term depression. Conclusion: Considering the importance of glutamate receptors (especially NMDA subtype), calcium homeostasis, balance between kinases and phosphatases, calcineurin, cellular adhesion molecules, extracellular matrix, glial cells, and different neurotransmitters in process of memory formation, this study evaluate the cellular and molecular pathways involved in learning and memory.

Keywords: Memory, Learning, Neuronal Plasticity, Long-Term Potentiation, Long-Term Synaptic Depression
Full-Text [PDF 319 kb]   (6106 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience



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Ghadiri T, Modarres Mousavi M, Alipour F, Mohammad Sadeghi S. Cellular and Molecular Pathways of Learning and Memory. Shefaye Khatam. 2014; 2 (2) :81-88
URL: http://shefayekhatam.ir/article-1-86-en.html


Volume 2, Issue 2 (Spring - 2014) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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