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Showing 5 results for Chronic Pain
Najme Vakili, Volume 2, Issue 3 (9-2014)
Abstract
People with post-traumatic stress disorder (PTSD) have been found to be at a higher risk for a number of mental and physical health problems. In addition to these problems, people with PTSD are more likely than those without PTSD to experience problems with pain. The purpose of this study was to determine the psychological profile of veterans with PTSD and chronic pain and its comparison with profiles of patients with chronic pain. This is a cross-sectional study and comparison. 100 veterans with chronic pain and PTSD and 100 chronic pain patients, who were referred to Pain Clinic in Tehran Khatam Hospital, were randomly selected and MMPI questionnaire was used to assess mental profile of this patients. The results showed that the psychological profile in all of MMPI scales were significantly different between the two groups (P<0.05) and the mean scores for all indicators in veterans with chronic pain and PTSD were significantly higher than from patients with chronic pain. The greatest differences were observed in the indices of hypochondriasis and depression. The results indicated that there are certain psychological profiles in patients with chronic pain. All of MMPI scales were significantly different between the two groups with the highest different in hypochondriasis and depression. The results suggest that there are certain psychological problems in veterans with chronic pain.
Pirhossein Kolivand, Azadeh Nazari Mahin, Robabeh Jafari, Volume 3, Issue 3 (10-2015)
Abstract
Introduction: Chronic pain is annoying and this may cause reduction of the patient's tolerance threshold. Patients suffering from chronic pain experience significant psychological symptoms. This study was aimed to investigate the effectiveness of behavioral-cognitive treatment on decreasing pain intensity in patients suffering from chronic pain. Materials and Methods: The sample of 30 patients diagnosed with chronic pain were divided into two groups, including 14 men and 16 women. Pain intensity evaluation questionnaire was used to collect data, the pre-test, post-test, and follow-up of both control and experimental groups were completed. Behavioral- cognitive treatment was performed during 8 sessions. Results: This study revealed that the mean pain intensity scores in post-test significantly decreased compared to pre-test values. Conclusion: Our results indicated that cognitive-behavioral treatment is effective on decreasing pain intensity in patient suffering from chronic pain.
Pirhossein Kolivand, Azadeh Nazari Mahin, Robabeh Jafari, Volume 3, Issue 3 (10-2015)
Abstract
Introduction: Chronic pain is a healthcare problem worldwide without any appropriate treatment. Effective compatibility with pain requires comprehensive compliance through all aspects of patient's life. Psychological factors are central to the experience of chronic pain and can minimize the restrictive effects of pain. Materials and Methods: Two experimental and control groups, consisting 15 people were selected among patients with chronic pain in Khatam-Alanbia hospital. Kessler K10 distress questionnaire was used in pre-and post-test evaluations. Results: A significant difference was observed in distress levels between experimental and control groups in pre- and post-test evaluation. The mean value of distress in experimental group was lower than control group in post- test evaluation. Conclusion: Cognitive behavioral therapy is an effective treatment in reduction of distress in patients suffering from chronic pain.
Nasrolah Nasr Heydarabadi, Reza Safdari, Marjan Ghazi Saeedi, Arash Rahman, Laleh Hakemi, Peirhossein Kolivand, Mobin Shaterian, Volume 4, Issue 3 (9-2016)
Abstract
Introduction: Pain is a major symptom in many medical conditions and is significantly associated with alteration of the quality of life and individual as well as overall performance. Pain is one of the main problems in patient with spinal cord injury. Spinal cord injury is one of the causes of chronic pain that occurs due to temporary or permanent changes in spinal cord function. Traffic accidents, war injuries and sports injuries are the major reasons. Clinical decision support system separates intelligently expert's information and knowledge for physician, health professionals, and patients as well as other individuals and represents the knowledge in right time to provide more efficient treatment and health care. Automated health information systems are gathering data and information to support the integration of managerial decision-making processes. Conclusion: Paper-based systems are not suitable for repetitive clinical evaluations of patients with spinal cord injury. Design and implementation of automated systems for gathering information in pain management and physician assistant to medical decision making for pain diagnosis in patients with spinal cord injury are very effective. This system may use different artificial intelligence techniques, including Bayesian networks, artificial neural network, decision trees, and fuzzy logic.
Fatemeh Younesi Soltani, Fateme Salahshor, Hassan Abbassian, Volume 5, Issue 2 (4-2017)
Abstract
Chronic pain is a prevalent and debilitating condition, conveying immense human burden. Suffering from chronic pain is not only caused by painful symptomatology, but also through a wide range of psychopathological and physical consequences, including depression and anxiety disorders, impaired sleep and cognition, cardiovascular morbidity and impaired sexual function, all contributing to diminished quality of life. Opioids are highly effective analgesics because they target both of sensory and emotional elements, by inhibiting pain pathways and alleviating negative affect (including depression) by engaging reward or hedonic pathways. Prolonged exposure to an opioid induces hyperalgesia and tolerance, which negatively affect pain management in turn and significantly hamper the application of opioids. Neuroinflammation occurs in a wide range of neurological disorders -from central nervous system (CNS) infection and trauma to neurodegenerative diseases and psychiatric disorders. Recently demonstrated that chronic opioid administration in rats induces a robust neuroinflammatory response via toll-like receptor 4 (TLR4) signaling in the periaqueductal gray (PAG), a key site for opioid-mediated analgesia, that drives tolerance. Morphine is a powerful analgesic for treating severe pain, Morphine tolerance is a complex physiologic process, and various mechanisms have been proposed, such as glutamatergic receptor activation and neuroinflammation. In various preclinical chronic pain models, cytokines and neurotrophic factors have been identified as pivotal mediators involved in neuroimmune activation pathways and cascades, and in neuron–glia interactions. Both chronic pain and chronic opioids promote neuroinflammation in limbic brain structures leading to the genesis of negative affective states. This negative effect may increase the likelihood of opioid misuse and addictive-like behaviors in the chronic pain population. Understanding the mechanisms underlying opioid-induced neuroinflammation is paramount to developing effective pain management strategies that minimize the risk of dependence, abuse, and long-term consequences of chronic neuroinflammation.
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