%0 Journal Article %A Saffarzadeh, Fatemeh %A Hadjighassem, Mahmoud Reza %T The Role of TRPV1 Receptors in the Brain Function %J The Neuroscience Journal of Shefaye Khatam %V 1 %N 4 %U http://shefayekhatam.ir/article-1-53-en.html %R 10.18869/acadpub.shefa.1.4.42 %D 2013 %K TRPV1 receptor, Synaptic Transmission, Neuronal Plasticity, %X Introduction: Transient receptor potential vanilloid 1 (TRPV1) belongs to a family of ligand gated ion channels. This non-selective cation channel is permeable to Na+, K+ and highly to Ca2+ ions. It acts as a trigger for Ca2+ mediated cell signaling. Although this channel has been previously found highly expressed in dorsal root ganglion, there is a line of evidence indicating the remarkable expression of TRPV1 channels in other parts of the central nervous system. Conclusion: There is evidence to suggest that TRPV1 channels in the brain contribute in many basic neuronal functions, including neurotransmitter release and synaptic plasticity. %> http://shefayekhatam.ir/article-1-53-en.pdf %P 42-49 %& 42 %! %9 Review --- Open Access, CC-BY-NC %L A-10-1-32 %+ Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. %G eng %@ 2322-1887 %[ 2013