@ARTICLE{Saeedi, author = {Saeedi, Chiman and }, title = {Investigation of Dysfunction in the Neural Systems Underlying Social Perception, Action Observation and Theory of Mind in Autism Spectrum Disorders}, volume = {6}, number = {2}, abstract ={Introduction: Autism spectrum disorders (ASD) are neurodevelopmental disorders that are characterized by difficulties in social communication and social interaction as well as by restricted and repetitive behaviors, interests or activities. Researches within the field of social neuroscience demonstrate that social functioning deficits in ASD may arise from dysfunctions in the neural systems that implicate in social information processing. In this study, existing research related to the neural basis of three key neural systems underlying social information processing (social perception, action observation, and theory of mind and malfunction of neural systems) in ASD have been reviewed. The results indicate that there is atypical activation in brain regions involved in social perception (the posterior superior temporal sulcus (PSTS), the amygdala, the orbitofrontal cortex, and the fusiform gyrus), in regions associated with action observation consist of mirror neurons system and its three interconnected areas (PSTS, the inferior frontal gyrus, and the inferior parietal lobule), and in regions assign to theory of mind (the medial prefrontal cortex, the tempro-parietal junction, PSTS, the posterior cingulate cortex/precuneus, and the anterior temporal lobes). Conclusion: These results indicate aberrant social information processing in ASD and define it as deficits in the neural systems involved in social perception, action understanding, and theory of mind. These findings provide a foundation for understanding the neural mechanisms underlying social deficits in ASD and highlight the role of PSTS as a common region in all three systems. }, URL = {http://shefayekhatam.ir/article-1-1476-en.html}, eprint = {http://shefayekhatam.ir/article-1-1476-en.pdf}, journal = {The Neuroscience Journal of Shefaye Khatam}, doi = {10.29252/shefa.6.2.82}, year = {2018} }