RT - Journal Article T1 - The Effect of Exercise on Parkinson's Disease JF - The-Neuroscience-Journal-of-Shefaye-Khatam YR - 2020 JO - The-Neuroscience-Journal-of-Shefaye-Khatam VO - 9 IS - 1 UR - http://shefayekhatam.ir/article-1-2131-en.html SP - 189 EP - 199 K1 - Exercise K1 - Parkinson Disease K1 - Neuroprotection AB - Introduction: The prevalence of early symptoms of Parkinson's disease, even in middle age and adolescence, has caused widespread concern. Physical activity is known as one of the non-pharmacological methods to reduce behavioral, motor, biochemical, cardiovascular, and mitochondrial dysfunctions in Parkinson's disease. Although the basis of such biological and molecular benefits is unknown, the antioxidant and anti-inflammatory properties of physical activity may improve the symptoms of Parkinson's disease. Conclusion: Although there is no definitive cure for Parkinson's disease, the use of medications along with adjunctive therapies, such as exercise, can be resulted in promising improvements. However, more research is required to achieve an exercise program that provides optimal benefits to patients' quality of life and reduces mortality. LA eng UL http://shefayekhatam.ir/article-1-2131-en.html M3 10.52547/shefa.9.1.189 ER -