The Neuroscience Journal of Shefaye Khatam
مجله علوم اعصاب شفای خاتم
Shefaye Khatam
Medical Sciences
http://shefayekhatam.ir
1
admin
2322-1887
2345-4814
10.61186/shefa
fa
jalali
1396
1
1
gregorian
2017
4
1
5
2
online
1
fulltext
en
O 13: Ion Channels in Autoimmune Neurodegeneration
O 13: Ion Channels in Autoimmune Neurodegeneration
تحقیقات پایه در علوم اعصاب
Basic research in Neuroscience
مروری
Review --- Open Access, CC-BY-NC
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<p style="margin-top: 0px; margin-bottom: 0px; text-align: center;"><span style="color: rgb(0, 0, 0); line-height: 20.8px;">لطفاً به چکیده انگلیسی مراجعه شود.</span></p>
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<p>Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. Ionic conductances regulate T cell activation as well as neuronal function and thus have been found to play a crucial role in MS pathogenesis. Since present therapeutical approaches are only partially effective so far, ion channel modulation as a future strategy was brought into focus. Here, we review the status quo concerning recent findings from ion channel research in MS and its animal model, experimental autoimmune encephalomyelitis. </p>
Multiple Sclerosis, Neuronal, Autoimmune
13
13
http://shefayekhatam.ir/browse.php?a_code=A-10-24-831&slc_lang=en&sid=1
Petra
Hundehege
Petra
Hundehege
Petra.Hundehege@ukmuenster.de
100319475328460011744
100319475328460011744
Yes
University Hospital Münster, Neurology Clinic and Institute of Translational Neurology, ICB Mendelstraße 7, 48149 Münster, Germany
University Hospital Münster, Neurology Clinic and Institute of Translational Neurology, ICB Mendelstraße 7, 48149 Münster, Germany