en P 93: The Role of Marine Compounds in Neuroinflammation تحقیقات پایه در علوم اعصاب Basic research in Neuroscience مروری Review --- Open Access, CC-BY-NC <table border="0" cellpadding="5px" cellspacing="2" dir="rtl" id="table_article" style="font-family: Tahoma; background-color: rgb(251, 250, 249); break-inside: avoid !important;" width="100%"> <tbody style="break-inside: avoid !important; font-size: 12px; margin-top: 0px; line-height: 2.2; margin-bottom: 0px; text-align: justify;"> <tr style="break-inside: avoid !important;"> <td class="abstractmed" colspan="2" style="break-inside: avoid !important;"> <p style="font-size: 12px; margin-top: 0px; margin-bottom: 0px; text-align: center;"><span style="color: rgb(0, 0, 0); font-size: 12px; line-height: 20.8px;">لطفاً به چکیده انگلیسی مراجعه شود.</span></p> </td> </tr> <tr style="break-inside: avoid !important;"> </tr> </tbody> </table> <p></p> <p>Extensive research in the last decade has defined that most chronic diseases display dysregulation of multiple cell signaling pathways that have been linked to inflammation. Neuroinflammation is reaction of living nervous tissue to injury. It may be initiated in response to neurological disease. Including infection, traumatic brain injury, toxic metabolites and autoimmunity. The natural compounds possessing anti neuroinflammation actions included: dietary fibers, lipids, antioxidants, phytochemicals, and microorganisms. The marine environment contains a wide range of biological and chemical diversity that can be applied to various aspects of food processing, storage, and fortification.&nbsp; Further, numerous marine invertebrates based compounds have biological activities and also interfere with the pathogenesis of diseases. Isolated ingredients from marine invertebrates have been shown to activity of pharmacological and are effective for the discovery of bioactive compounds. Many&nbsp;of&nbsp;these compounds (polyunsaturated fatty acids (PUFAs), sterols, proteins, polysaccharides, antioxidants, and pigments) have biologically or pharmacological&nbsp;activity.&nbsp; Role of these compounds in neuroscience research and development of new therapies targeting the central nervous system will be addressed, with particular focus on neuroinflammation. Marine natural products are chemical multiple-target molecules obtain in animals and plants, and microorganisms.</p> Marine compounds, Neuroinflammation, Neuroscience 124 124 http://shefayekhatam.ir/browse.php?a_code=A-10-24-943&slc_lang=en&sid=1 Robabeh Jafari Robabeh Jafari robabehjafari@gmail.com 100319475328460012080 100319475328460012080 Yes Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Beheshteh Azhdari Beheshteh Azhdari 100319475328460012081 100319475328460012081 No Department of Marine Chemistry, Faculty of Basic Sciences, University of Chabahar Maritime and Marine Sciences, Chabahar, Iran Department of Marine Chemistry, Faculty of Basic Sciences, University of Chabahar Maritime and Marine Sciences, Chabahar, Iran Maryam Jafari Maryam Jafari 100319475328460012082 100319475328460012082 No Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Zahra Aeini Zahra Aeini 100319475328460012083 100319475328460012083 No Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Sara Abdolahi Sara Abdolahi 100319475328460012084 100319475328460012084 No Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Ali Jahanbazi Jahan Abad Ali Jahanbazi Jahan Abad 100319475328460012085 100319475328460012085 No Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran Shefa Neuroscience Research Center, Khatam-al-Anbia Hospital, Tehran, Iran