fa P90: Methamphetamine and Traffic Accidents نوروفارماکولوژی Neuropharmacology مروری Review --- Open Access, CC-BY-NC <p align="center">لطفاً به چکیده انگلیسی مراجعه شود. </p> Methamphetamine hydrochloride is a white to light brown crystalline powder, or clear chunky crystals resembling ice. The majority of street methamphetamine is produced in clandestine laboratories. The drug manufacturer states that patients should be informed that methamphetamine and amphetamine may impair the ability to engage in potentially hazardous activities such as driving a motor vehicle. In epidemiology studies drive-off-the-road type accidents, high speed, failing to stop, diminished divided attention, inattentive driving, impatience, and high risk driving have been reported. Significant impairment of driving performance would also be expected during drug withdrawal. In a recent review of 101 driving under the influence cases, where methamphetamine was the only drug detected, blood concentrations ranged from <0.05-2.36 mg/L (mean 0.35 mg/L, median 0.23 mg/L). Driving and driver behaviors included speeding, lane travel, erratic driving, accidents, nervousness, rapid and non-stop speech, unintelligible speech, disorientation, agitation, staggering and awkward movements, irrational or violent behavior, and unconsciousness. Impairment was attributed to distraction, disorientation, motor excitation, hyperactive reflexes, general cognitive impairment, or withdrawal, fatigue and hyper somnolence. Road Traffic Accident, Methamphetamine, Drug Abuse 140 140 http://shefayekhatam.ir/browse.php?a_code=A-10-24-489&slc_lang=fa&sid=1 Mohammadesmaiel Alipour Mohammadesmaiel Alipour 10031947532846006072 10031947532846006072 No a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. Maryam Jafarian Maryam Jafarian jafarian.m34@gmail.com 10031947532846006073 10031947532846006073 Yes a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.