[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Home::
Journal Information::
Articles Archive::
Guide for Authors::
For Reviewers::
Ethical Statements::
Registration::
Site Facilities::
Contact us::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Copyright Policies

 

AWT IMAGE

 

..
Open Access Policy

This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

..
:: Volume 5 - The Spring Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2017, 5 - The Spring Supplement of Shefaye Khatam 2 -: 123-123 Back to browse issues page
P 92: A Critical Balance between Repair and Demolish of Proinflammatory Factors to Improve Effects of Neuroinflammation
Mahtab Irani * , Fatemeh Yardehnavi , Zohreh J Memari
a. Islamic Azad University, Mashhad Branch, Mashhad, Iran b. Member of Mashhad Neuroscience Research Group of Islamic Azad University, Mashhad Branch, Mashhad, Iran , irani.m1372@gmail.com
Abstract:   (3341 Views)

One of the most important problems in neuroscience researches is the understanding what is the communication between the immune system and central nervous system. Proinflammatory factors play an important role in this communication. The dysregulation of proinflammatory factors such as cytokines and chemokines is a central feature in the development of neuroinflammation.one of the important  cytokines is tumor necrosis factor superfamily molecules that role of this cytokine is in the activation, proliferation, differentiation ,and migration of immune cells into the central nervous system. Another important cytokines especially in the onset of inflammatory process is interleukin-1 because of overexpression of this factor which affects with produces many reactions that cause dysfunction and neuronal death. Neuroinflammation is inflammation of the nervous tissue and it is immune response to variety of cues such as infection, toxic metabolites, traumatic brain injury, or autoimmunity. The central nervous system is an immunologically privileged site because the role of blood brain barrier, it has special structure that is composed of astrocytes and endothelial cells. This review will focus on how proinflammatory factors affect neuroinflammation process.

Keywords: Neuroinflammation, Proinflammatory, Cytokine
Full-Text [PDF 213 kb]   (998 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Irani M, Yardehnavi F, J Memari Z. P 92: A Critical Balance between Repair and Demolish of Proinflammatory Factors to Improve Effects of Neuroinflammation. Shefaye Khatam 2017; 5 (S2) :123-123
URL: http://shefayekhatam.ir/article-1-1279-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 5 - The Spring Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645