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:: Volume 6 - The Summer Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2018, 6 - The Summer Supplement of Shefaye Khatam 2 -: 34-34 Back to browse issues page
P7: The Role of Aquaporins in Synaptic Plasticity and Epilepsy
Zeinab Najmi , Mostafa Modarres Mousavi *
Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran , modarres.mousavi@gmail.com
Abstract:   (3215 Views)
Introduction: One family of small integral membrane proteins called "aquaporins" have crucial role in water transport. Aquaporin-4 (AQP4), a double-sided water channel protein, shows the highest levels of AQP4 in the central nervous system. AQP4 binds to a subset of potassium channels such as Kir4.1 and Kir5.1, which can affect synaptic transmission. Conclusion: Thus, AQP4 have crucial role in alterations of synaptic plasticity and cognition which implicated in diverse neurological diseases such as epilepsy.
Keywords: Synaptic Plasticity, Water Channel, Synaptic Transmission, Aquaporins
Full-Text [PDF 236 kb]   (691 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience

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Najmi Z, Modarres Mousavi M. P7: The Role of Aquaporins in Synaptic Plasticity and Epilepsy. Shefaye Khatam 2018; 6 (S2) :34-34
URL: http://shefayekhatam.ir/article-1-1794-en.html
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6 - The Summer Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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