[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Home::
Journal Information::
Articles Archive::
Guide for Authors::
For Reviewers::
Ethical Statements::
Registration::
Site Facilities::
Contact us::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Copyright Policies

 

AWT IMAGE

 

..
Open Access Policy

This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

..
:: Volume 1, Issue 3 (Summer - 2013) ::
Shefaye Khatam 2013, 1(3): 5-10 Back to browse issues page
Protective Effect of Soy on Movement Disorders Induced by Parkinson Disease in Ovariectomized Animal Model
Hadi Aligholi * , Maryam Safahani , Alireza Sarkaki , Reza Amani
a. Neuroscience Group, School of Advanced Technologies In Medicine, Tehran University of Medical Sciences, Tehran, Iran. b. Physiology Group, Medical Faculty, Ahwaz Jondishapoor University of Medical Sciences, Ahwaz, Iran. c. Shefa Neuroscience Research Center, Tehran, Iran. , hadialigholi@yahoo.com
Abstract:   (10787 Views)

Introduction: Investigations have shown that ovarian steroids are involved in reduction of movement disorders during neurodegenerative diseases especially Parkinson's disease. These steroids have many side effects, thus, other estrogenic agents with fewer side effects are needed to develop alternative treatment strategies. The main objection of this study was to evaluate the effects of soy meal on movement disorders in ovariectomized animal model of Parkinson's disease. Materials & Methods: Animals were divided into 3 groups: intact, treated by normal diet and treated by soy meal diet. Female Wistar rats with the exception of intact group were ovariectomized at the first line of study. Then Stride length test was done and animals received special diet for 4 weeks post substantia nigra pars compacta (SNc) electrical lesion. At the end, Stride length and Morpurgo's test was performed. Results: Soy meal diet in ovariectomized rats with SNc Lesion improved muscle stiffness without any effect on stride length. Conclusion: Our results suggest that soy meal is a potential alternative to estrogen in the treatment of Parkinson’s disease.

Keywords: Parkinson Disease, Soy Foods, Ovariectomy, Rats
Full-Text [PDF 2247 kb]   (2919 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Neurology



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aligholi H, Safahani M, Sarkaki A, Amani R. Protective Effect of Soy on Movement Disorders Induced by Parkinson Disease in Ovariectomized Animal Model. Shefaye Khatam 2013; 1 (3) :5-10
URL: http://shefayekhatam.ir/article-1-39-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 3 (Summer - 2013) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645