[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Home::
Journal Information::
Articles Archive::
Guide for Authors::
For Reviewers::
Ethical Statements::
Registration::
Site Facilities::
Contact us::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Copyright Policies

 

AWT IMAGE

 

..
Open Access Policy

This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

..
:: Volume 2 - The Autumn Supplement of Shefaye Khatam 3 - ::
Shefaye Khatam 2014, 2 - The Autumn Supplement of Shefaye Khatam 3 -: 46-46 Back to browse issues page
W3: A Controllable Brain Injury Model with a Defined Size for Evaluation of Tissue Engineered Products
Hadi Aligholi * , Maryam Safahani , Sajad Sahab Negah , Mostafa Modarres Mousavi
a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran. b. Department of Neuroscience, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran. , aligholihadi@gmail.com
Abstract:   (4864 Views)
Brain injury has a multiple pathophysiology for which there is no definite treatment. In this regard, tissue engineering is one of the probable strategies for repair of damaged tissue. But creating a proper model for testing the engineered products faced some difficulties, specially, when we want to evaluate the effects of a product on the volume of injury. The current brain injury methods couldn’t provide defined brain tissue damage. We propose a new method to solve the problem. Previously, we introduced a new method for harvesting subventricular tissue from adult rat brain using a modified semi-automatic biopsy needle. We showed that a defined volume of tissue harvested from a specific area of brain without any adverse effect on other regions. We suggest using this biopsy procedure for creating a brain injury model with a defined size. Using this controllable biopsy method, we can test engineered products in a rat model of brain injury and assessed the volume of cavity after performing treatments in different groups.
Keywords: Brain Injury, Subventricular Tissue, Biopsy
Full-Text [PDF 200 kb]   (1600 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Neurosurgery


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aligholi H, Safahani M, Sahab Negah S, Modarres Mousavi M. W3: A Controllable Brain Injury Model with a Defined Size for Evaluation of Tissue Engineered Products . Shefaye Khatam 2014; 2 (S3) :46-46
URL: http://shefayekhatam.ir/article-1-505-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 2 - The Autumn Supplement of Shefaye Khatam 3 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645