TY - JOUR T1 - The Role of Micro-RNAs in Post-Traumatic Stress Disorder TT - نقش micro-RNA ها در اختلال اضطرابی پس از ضربه JF - The-Neuroscience-Journal-of-Shefaye-Khatam JO - The-Neuroscience-Journal-of-Shefaye-Khatam VL - 6 IS - 1 UR - http://shefayekhatam.ir/article-1-1437-en.html Y1 - 2018 SP - 49 EP - 60 KW - Stress Disorders KW - Post-Traumatic KW - Amygdala KW - Hippocampus KW - Prefrontal Cortex N2 - Introduction: Post-traumatic stress disorder (PTSD) is a form of anxiety disorders. PTSD typically follows an exposure to severe stress. It is characterized by a particular clinical syndrome, including re-experiencing symptoms and alterations in arousal, avoidance, cognition, and mood conditions. Recent evidences propose that micro-RNAs are crucial epigenetic players in mental disorders. It has been demonstrated that micro-RNAs are promising non-invasive biomarkers for different mental health disorders. It has been reported that the levels of micro-RNAs have been changed in psychotic diseases, including Alzheimer's disease and PTSD. Conclusion: Micro-RNAs seem to play a role in pathophysiology of psychological diseases. In this article, we discussed the new findings suggesting a relationship between micro-RNAs and PTSD as well as the possible roles of micro-RNAs in diagnosis and treatment of this mental disorder. M3 10.29252/shefa.6.1.49 ER -