en O25: Treatment of Autoimmune Epilepsy تحقیقات پایه در علوم اعصاب Basic research in Neuroscience مروری Review --- Open Access, CC-BY-NC <div style="text-align: center;"><span style="text-align: center; color: rgb(0, 0, 0); text-transform: none; text-indent: 0px; letter-spacing: normal; font-family: Tahoma; font-size: 12px; font-style: normal; font-weight: 400; word-spacing: 0px; float: none; display: inline !important; white-space: normal; orphans: 2; widows: 2; background-color: rgb(251, 250, 249); font-variant-ligatures: normal; font-variant-caps: normal; -webkit-text-stroke-width: 0px; text-decoration-style: initial; text-decoration-color: initial;">لطفاً به چکیده انگلیسی مراجعه شود.</span></div> <p style="text-align: justify;">Seizure and epilepsy can be related to autoimmune diseases and processes. Accurate diagnosis is essential for better treatment of these conditions. Different clinical studies have been conducted to diagnose and treat autoimmune epilepsy. Rapid treatment of these diseases helps to Improve prognosis and less relapses. Conventional epilepsy treatments including antiepileptic drugs are less successful in these cases. Early first line immunotherapy (corticosteroids, intravenous immunoglobulin, plasma exchange<span></span>) provides fair response to autoimmune encephalitides but half or more patients require a second-line immunotherapy. (Rituximab, Cyclophosphamide). A significant percentage of patients are resistant to first and second line immunotherapy and require further treatment.</p> Autoimmune Epilepsy, Treatment, Immunotherapy 25 25 http://shefayekhatam.ir/browse.php?a_code=A-10-24-1098&slc_lang=en&sid=1 Mohammad Taghi Farzadfard Mohammad Taghi Farzadfard farzadfardmt@mums.ac.ir 100319475328460015423 100319475328460015423 Yes Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran Department of Neurology, Mashhad University of Medical Sciences, Mashhad, Iran