en P155: The Role of Vegan Diet in Epilepsy تحقیقات پایه در علوم اعصاب Basic research in Neuroscience مروری Review --- Open Access, CC-BY-NC <div style="text-align: center;"><span style="background:#FBFAF9;"><span style="color:black;"><span style="font-family:tahoma,sans-serif;"><span style="font-size:9.0pt;">لطفاً به چکیده انگلیسی مراجعه شود</span></span></span></span><span dir="LTR" style="background:#FBFAF9;"><span style="color:black;"><span style="font-family:tahoma,sans-serif;"><span style="font-size:9.0pt;">.</span></span></span></span></div> <div style="text-align: justify;">Food habits have a serious role in the emergence of the diseases and inflammation that causes many kinds of diseases. Some case-control studies concluded that high animal fat and cholesterol in diet is associated with some neuroinflammatory diseases such as Parkinson and Alzheimer. High level of cholesterol and lipopolysaccharides(LPS) include the peripheral inflammation in the body. There is evidence that activation of immune and inflammatory processes occurs in a variety of epilepsies. Also, there are animal trials that show peripheral inflammation can cause the NeuroInflammation and oxidative stress and in this condition, activation of microglial cells and producing inflammatory cytokines have an important role in epileptic disorders. LPS-induced Peripheral inflammation evokes NeuroInflammation in the hippocampus and increases the seizure susceptibility. On the other hand, studies show the vegetarianism can obviously reduce the level of inflammation. level of inflammation by the anti-inflammatory effect of vegan diet and some eastern diets which decrease peripheral inflammation and consequently mitigate the neuro inflammation and neuropathy, the main causes of epileptic disorders. It seems vegan diet or diets with a low level of LPS or animal fat can be a reducing factor in epilepsy seizers.</div> Epilepsy, Vegan Diet, Inflammation, Neuro Inflammation 186 186 http://shefayekhatam.ir/browse.php?a_code=A-10-24-1204&slc_lang=en&sid=1 Sara Abbasi Sara Abbasi maah.titi.1997297@gmail.com 100319475328460016214 100319475328460016214 Yes Mashhad University of Medical Sciences, Mashhad, Iran Mashhad University of Medical Sciences, Mashhad, Iran Motahareh Mirdoosti Seyedeh Motahareh Mirdoosti 100319475328460016215 100319475328460016215 No Mashhad University of Medical Sciences, Mashhad, Iran Mashhad University of Medical Sciences, Mashhad, Iran Hojjat Shadman Zahroodi Hojjat Shadman Zahroodi 100319475328460016216 100319475328460016216 No Mashhad University of Medical Sciences, Mashhad, Iran Mashhad University of Medical Sciences, Mashhad, Iran Mohammad Mirzaei Mohammad Mirzaei 100319475328460016217 100319475328460016217 No Mashhad University of Medical Sciences, Mashhad, Iran Mashhad University of Medical Sciences, Mashhad, Iran