Cancer is one of the most common diseases in the world. One of the important psychological factors in these patients is a death anxiety. So this study aimed to investigate death anxiety in patients with cancer in Kermanshah. In this cross-sectional study that was performed on 101 patients with cancer that referred to the oncology department of Imam Reza Hospital, we used Templer Death Anxiety and Demographic Scale and finally data analyzed by using SPSS version 22. The results showed that 64.35% and 88.11% of patients were female and married respectively. The average scores of death anxiety were 9.71. 81.18% of the patients had high death anxiety. Finally, the results showed that death anxiety in this study was significant relationship with some demographic information. The findings indicate high score anxiety of death in the majority of patients with cancer. Due to the high death anxiety in these patients and its psychological effects, psychological interventions and counseling to relieve death anxiety by psychologist is necessary on Oncology departments.