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:: Volume 5 - The Spring Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2017, 5 - The Spring Supplement of Shefaye Khatam 2 -: 13-13 Back to browse issues page
O 13: Ion Channels in Autoimmune Neurodegeneration
Petra Hundehege *
University Hospital Münster, Neurology Clinic and Institute of Translational Neurology, ICB Mendelstraße 7, 48149 Münster, Germany , Petra.Hundehege@ukmuenster.de
Abstract:   (3409 Views)

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. Ionic conductances regulate T cell activation as well as neuronal function and thus have been found to play a crucial role in MS pathogenesis. Since present therapeutical approaches are only partially effective so far, ion channel modulation as a future strategy was brought into focus. Here, we review the status quo concerning recent findings from ion channel research in MS and its animal model, experimental autoimmune encephalomyelitis. 

Keywords: Multiple Sclerosis, Neuronal, Autoimmune
Full-Text [PDF 200 kb]   (782 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Hundehege P. O 13: Ion Channels in Autoimmune Neurodegeneration. Shefaye Khatam 2017; 5 (S2) :13-13
URL: http://shefayekhatam.ir/article-1-1167-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 5 - The Spring Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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