[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 5 - The Spring Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2017, 5 - The Spring Supplement of Shefaye Khatam 2 -: 91-91 Back to browse issues page
P 60: The Effect of Melatonin as a Therapeutic Goal on Multiple Sclerosis Through Immune Processes
Mona Abdollahi *
a. Islamic Azad University, Mashhad Branch, Mashhad, Iran b. Member of Mashhad Neuroscience Research Group of Islamic Azad University, Mashhad Branch, Mashhad, Iran , mona.abdollahi73@yahoo.com
Abstract:   (1301 Views)

Multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. The imbalance between the T cell effectors and T cell regulators is thought to have a role in the pathogenesis of the disease. Melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. Melatonin has an effect on the regulatory T cells and cytokines that suggests its role as a therapeutic target. The researchers experimented that melatonin is reduced in some MS patients which could increase pro-inflammatory cytokines such as TNFα. We review the effect of melatonin on the immune system and clinical symptoms of MS patients. The purpose of this study was to determine the effect of melatonin in improvement the symptoms and down regulation in the immune system of MS patients.

Keywords: Melatonin, Multiple sclerosis, Immune processes
Full-Text [PDF 203 kb]   (347 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

abdollahi M. P 60: The Effect of Melatonin as a Therapeutic Goal on Multiple Sclerosis Through Immune Processes. Shefaye Khatam. 2017; 5 (S2) :91-91
URL: http://shefayekhatam.ir/article-1-1246-en.html


Volume 5 - The Spring Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 32 queries by YEKTAWEB 4215