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Shefaye Khatam 2017, 5 - The Spring Supplement of Shefaye Khatam 2 -: 102-102 Back to browse issues page
P 71: A Review on the Role and Efficacy of Vitamins in Depression
Vahid Mahdavizade *
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , mahdavizadev@yahoo.com
Abstract:   (1178 Views)

Depression, as a mental disorder, affects more than 300 million people of all ages every year. It is said to be associated with neuroinflammation. Depression has affected women more than men. Over the world, people are disabled due to depression rather than any other condition. Neuroinflammation is the brain’s reaction to injury. Apparently there is a link between neuroinflammation and depression. Vitamins have a prominent effect on brain-related diseases such as depression. This review was done to determine the relationship of neuroinflammation and depression and in order to analyze role of vitamins on it. Vitamin B1 is said to be effective in improving depression. The role of vitamin B2, however, is not clearly figured out, some studies showed it is effective while others show the opposite. Vitamin B3 is proved to have a role in depression, although further investigation is needed to realize the relationship. One study showed that B6 is no better than a placebo in treatment of depression although in another study it was observed that deficiency of pyridoxine is related to symptoms of depression. There was observed a conflict in the role of folic acid, some studies suggested its role in improving depression while others stated that it may not reduce the condition’s signs. Such a conflict exists in the matter of vitamin B12. Further studies is advised to assure the idea that B17 may have an effect on depression due to the conflicting results of different studies.

Keywords: Depression, Neuroinflammation, Vitamins
Full-Text [PDF 204 kb]   (351 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Mahdavizade V. P 71: A Review on the Role and Efficacy of Vitamins in Depression. Shefaye Khatam. 2017; 5 (S2) :102-102
URL: http://shefayekhatam.ir/article-1-1257-en.html


Volume 5 - The Spring Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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