[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
Main Menu
Home::
Journal Information::
Articles Archive::
Guide for Authors::
For Reviewers::
Ethical Statements::
Registration::
Site Facilities::
Contact us::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Copyright Policies

 

AWT IMAGE

 

..
Open Access Policy

This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

..
:: Volume 6 - The Spring Supplement of Shefaye Khatam 1 - ::
Shefaye Khatam 2018, 6 - The Spring Supplement of Shefaye Khatam 1 -: 1-1 Back to browse issues page
O1: Modeling of Mesenchymal Stem Cell-Derived Magnetite Nanoparticles for The Rehabilitation of Immune System Function and Reducing Inflammation and Promoting Myelination in the Treatment of MS Disease
Parvin Pourmasoumi * , Behnamoddin Jameie
Biomedical Engineering Department, Science and Research Branch of Islamic Azad University, Tehran, Iran , Pari.pourmasoumi@gmail.com
Abstract:   (3120 Views)
By Using the modeling of the mesenchymal (bone marrow) stem cell nanoparticles, the reinstatement of the immune system leads to the treatment of MS, result in the formation of a new immune system for the body by stem cell. The presence of stem cells promotes and strengthens myelination, and that, using simulation and 3D modeling, stem cells can be transmitted correctly to the target and place of injury and the location of inflammation. Using mathematical modeling and magnetic resonance images and 3D simulation of magnetite nanoparticles that carry stem cells and direct its guidance and modeling the new immune system to improve the function of immune cells and protect myelin in nerve cells and reduce inflammation from the modeling model provides a predetermined data that makes the pathway that the stem cell passes through in a patient that results in higher accuracy and ease of work. Modeling shows that stem cell infiltration can be better controlled by nanoparticles, and the presence of mesenchymal stem cells (BMSCs) plays a major role in rebuilding the immune system and reducing inflammation, and the presence of stem cells to generate signals with surrounding cells Being nervous and restoring the immune system reduces inflammation and thus restores myelin in the central nervous system and the spinal cord. Modeling the pathway in which the nano-particle carrying a stem cell that needs to travel to the site of a damaged lesion in the brain and spinal cord has a pre-designed and planned map that provides better controlled transmission in inflammation. It reduces inflammation and rebuilds the myelin, and its pathway can be seen in MRI images and can be captured at a molecular cellsurface.
Keywords: Magnetite Nanoparticles, Mesenchymal Stem Cells, MS, Modeling
Full-Text [PDF 238 kb]   (942 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Pourmasoumi P, Jameie B. O1: Modeling of Mesenchymal Stem Cell-Derived Magnetite Nanoparticles for The Rehabilitation of Immune System Function and Reducing Inflammation and Promoting Myelination in the Treatment of MS Disease. Shefaye Khatam 2018; 6 (S1) :1-1
URL: http://shefayekhatam.ir/article-1-1514-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6 - The Spring Supplement of Shefaye Khatam 1 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.05 seconds with 45 queries by YEKTAWEB 4645