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Shefaye Khatam 2018, 6 - The Spring Supplement of Shefaye Khatam 1 -: 155-155 Back to browse issues page
P124: Listeriosis in Central Nervous System
Somayeh Monazzah Harsini *
Department of Pathology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran , somayehmonazah@gmail.com
Abstract:   (972 Views)
Listeriosis is one of the CNS inflammatory diseases which is happened majority in the form of sporadic. Listeriosis is ingested with the food. Infection occurrence in an exposed person depends on the number of organisms ingested, the virulence of the organisms strain and the individual condition. It is known that Listeriosis has decisive importance as an infection which the cellular immunodefense mediated by the T lymphocyte is disturbed. Even patients without previous disease worth indicating may be affected. The attribute of the many CNS manifestations are illustrated via the case histories (meningoencephalitis, acute meningitis, brain abscess, brain stem encephalitis, chronic recidivating encephalitis, meningoencephalitis with infected cerebral infarct). Neurological signs, combined with CSF findings atypical for bacterial CNS disease, must not be taken and may point to listeriosis even though they arenchr('39')t specific for CNS listeriosis. The conclusive evidence is the proof of the Listeria in the blood or CSF or the proof of antibody titre changes in the serum. New CSF diagnostic procedure like CSF lactate determination and the recognition of IgG-positive B lymphocytes are suitable in differentiating between viral and noninflammatory CNS disease; the most important for consistency are repeation of CSF examinations. The therapy of choice in CNS listeriosis is high-dosage amoxycillin or ampicillin treatment combined with gentamycin. Estimation of chances of the listeriosis in CNS depends on the prior to disease in each case. The high mortality is at least in part due to delayed diagnosis.
Keywords: Listeriosis, Nervous System, CNS
Full-Text [PDF 263 kb]   (202 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Monazzah Harsini S. P124: Listeriosis in Central Nervous System. Shefaye Khatam. 2018; 6 (S1) :155-155
URL: http://shefayekhatam.ir/article-1-1590-en.html


Volume 6 - The Spring Supplement of Shefaye Khatam 1 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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