It shows that a possible relationship between anxiety and dissociation disorder. Dissociative disorder includes dissociative amnesia, depersonalization and the realization that they can occur when a person exposes to severe psychiatric stressful events that they have strong negative emotion for him and then he cannot cope with them, so use unsuitable strategies for coping such as memory loss (dissociative amnesia) in order to separate some aspect of traumatic stressful events. In this case report, we presented an 86-year-old man who was presented to the emergency medicine by GI Bleeding because of Ileocecal mass, finally right hemicolectomy and chemotherapy were done. Hospitalization like a traumatic experience increased his anxiety and amnesia of the stressful events that he experienced in this period was occurred. He couldn't remember the specific aspects of his surgery process and hospitalization. Unfortunately, clinicians focused on physical symptoms as the main clinical plan and mental illnesses usually was ignored. Dissociative experiences are life-threatening and can worsen the condition and severity of somatic illness.  Such conditions are not uncommon thus routine evaluation of presenting these symptoms is necessary in clinical setting in order to help people to retrieve their memory.