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Shefaye Khatam 2018, 6 - The Spring Supplement of Shefaye Khatam 1 -: 184-184 Back to browse issues page
P153: Evaluating the Effect of Lactobacillus Acidophilus Probiotic Supplementation on Sensory-Motor Recovery After a Traumatic Brain Injury
Ali Mehri, Amirhossein Heidari, Mohammad Moein Vakilzadeh, Sara Pasban Bovanlo, Ali Gorji, Sajad Sahab Negah *
a. Neuroscience Department, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran b. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran , sahabnegahs@mums.ac.ir
Abstract:   (906 Views)
Traumatic brain injury (TBI) is a common cause of death which affects millions of people around the world. TBI is also associated with various neurological impairments. After the primary mechanical injury at the moment of a TBI event, several cellular and molecular processes are activated within the brain tissue as the secondary injury. An important mechanism involved in the secondary injury of TBI is Neuroinflammation. Therefore, neuroinflammation offers a promising avenue for therapeutic intervention with the aim of preventing progressive neurodegeneration and improving the neurological recovery after TBI. A number of studies have shown the efficacy of probiotics in modulating inflammatory responses; however, it is still unclear if probiotics have the ability to regulate neuroinflammation, and more research is needed to determine the effect of probiotics on neuroinflammation and neurological recovery. If proven beneficial, probiotics offer a non-invasive, safe and cheap therapy for regulating post-TBI neuroinflammation. Multiple studies have demonstrated the ability of probiotics in decreasing inflammatory cytokines while also increasing the anti-inflammatory cytokines. Therefore, we hypothesize that using probiotics after TBI may have the capacity to modulate neuroinflammatory response and as a result, improve the neurological recovery.
Keywords: Neuroinflammation, Probiotics, Traumatic Brain Injury, TBI, Sensory-Motor Recovery
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Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Mehri A, Heidari A, Vakilzadeh M M, Pasban Bovanlo S, Gorji A, Sahab Negah S. P153: Evaluating the Effect of Lactobacillus Acidophilus Probiotic Supplementation on Sensory-Motor Recovery After a Traumatic Brain Injury. Shefaye Khatam. 2018; 6 (S1) :184-184
URL: http://shefayekhatam.ir/article-1-1656-en.html


Volume 6 - The Spring Supplement of Shefaye Khatam 1 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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