[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit ::
:: Volume 6 - The Summer Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2018, 6 - The Summer Supplement of Shefaye Khatam 2 -: 40-40 Back to browse issues page
P13: Aquaporins Function as a Novel Therapeutic Strategy for a Variety of Cerebral Disorders
Zeinab Najmi *, Mostafa Modarres Mousavi Sayed
Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
Abstract:   (1050 Views)
Introduction: Some cells have specialized channels in their plasma membranes that allow water to be transported though the lipid bilayer much more expeditiously than by simple diffusion which said “aquaporins”.  The aquaporins are a family of membrane proteins that perform as water channels in several cell varieties and tissues in which fluid transport is crucial, like the gastrointestinal tract, lung, secretory glands, and brain. A family of transmembrane molecules knowns as aquaporins facilitate the movement of water across cellular compartments. Conclusion: The critical role of Aquaporin-4 (AQP4) is in mediating water fluxes in response to neuronal activity and maybe in seizure-induced edema. Therefore, function or expression modulation of AQP4 in a variety of brain disorders includinghydrocephalus, tumor, stroke, and epilepsy can be suggested as a new therapeutic strategy.
Keywords: Therapeutic Strategy, Aquaporins, Epilepsy, Water Channels
Full-Text [PDF 237 kb]   (177 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Najmi Z, Modarres Mousavi M. P13: Aquaporins Function as a Novel Therapeutic Strategy for a Variety of Cerebral Disorders. Shefaye Khatam. 2018; 6 (S2) :40-40
URL: http://shefayekhatam.ir/article-1-1819-en.html


Volume 6 - The Summer Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
Persian site map - English site map - Created in 0.04 seconds with 32 queries by YEKTAWEB 4212