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:: Volume 6, Issue 4 (Autumn - 2018) ::
Shefaye Khatam 2018, 6(4): 1-4 Back to browse issues page
Axon Guidance Proteins: A Novel Target Point for Temporal Lobe Epilepsy
Sajad Sahab Negah *, Ali Jahanbazi Jahan-Abad, Mostafa Modarres Mousavi Sayed
a. Department of Neuroscience, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. b. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran , sahabnegahs@mums.ac.ir
Abstract:   (2328 Views)
Introduction: Epilepsy is primarily a neuronal network disorder characterized by recurrent and unpredictable seizures. Epilepsy is not only characterized by marked changes in ion channels but also by the abnormal synaptic protein expression. It has been reported that the expression of axon guidance proteins was changed in experimental models of epilepsy. In this letter to the editor, we review and discuss the changes of axon guidance proteins in epilepsy. Conclusion: Collectively, further insight into dysregulation of axon guidance proteins may help to develop novel therapeutic strategies for epilepsy.
Keywords: Axon Guidance, Epilepsy, Hippocampus
Full-Text [PDF 459 kb]   (688 Downloads)    
Type of Study: Letter to Editor --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience
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Sahab Negah S, Jahanbazi Jahan-Abad A, Modarres Mousavi M. Axon Guidance Proteins: A Novel Target Point for Temporal Lobe Epilepsy. Shefaye Khatam. 2018; 6 (4) :1-4
URL: http://shefayekhatam.ir/article-1-1825-en.html

Volume 6, Issue 4 (Autumn - 2018) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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