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:: Volume 7, Issue 2 (Spring - 2019) ::
Shefaye Khatam 2019, 7(2): 1-12 Back to browse issues page
Effect of Transcranial Direct Current Stmulation on the Response Inhibition in Patient with Obsessive Compulsive Disorder
Mahsa Shahmohammadi Kaleybar *, Hasan Bafandeh, Rahim Yousefi, Reza Rahbaran
Department of Cognitive Psychology, Azarbaijan Shahid Madani University,Tabriz, Iran , Mahsa Shahmohammadi773@yahoo.com
Abstract:   (879 Views)
Introduction: Transcranial Direct Current Stimulation (tDCS) can improve or impair the function of the brain. Deficiency in response inhibition has been considered as one of the causes of psychiatric disorders, such as obsessive-compulsive disorder (OCD). The present investigation scrutinized the effect of transcranial direct current stimulation through simultaneous uni-side anodal on response inhibition in patients suffering from OCD. Materials and Methods: The participants were 25 patients who referred to Counseling Center of the Azarbaijan Shahid Madani University in 1396. The participants were divided in two groups and received two different types of stimulations; anodal and sham stimulations on F3 area as well as cathode stimulation on the orbitofrontal cortex (ten 20-minute 2mA tDCS sessions). Results: The results revealed that application of tDCS through simultaneous anodal significantly improved response inhibition in patients suffering from OCD. Conclusion: The findings have shown that application of anodal tDCS can improve the response inhibition in OCD patients, possibly via enhancement of excitability in the prefrontal cortex.
Keywords: Transcranial Direct Current Stimulation, Patients, Prefrontal Cortex
Full-Text [PDF 1004 kb]   (374 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Neurophysiology
References
1. American Psychiatric Association (APA). The diagnostic and statistical manual of mental disorders(DSM-5). 5th ed. Wasington, DC: American Psychiat Association, Published. 2013.
2. Real E, Montejo A, Alonso P, Menchon JM. Sexuality and obsessive-compulsive disorder: the hidden affair. Neuropsychiat Res. 2013; 3(1): 23-31. [DOI:10.2217/npy.12.72]
3. Grados MA, Walkup J, Walford S. Genetics of obsessive-compulsive disorders: new findings and challenges. Brain Dev. 2003; 25: S55-S61. [DOI:10.1016/S0387-7604(03)90010-6]
4. Kühn S, Kaufmann C, Simon D, Endrass T, Gallinat J, Kathmann N. Reduced thickness of anterior cingulate cortex in obsessive-compulsive disorder. Cortex. 2013; 49(8): 2178-85. [DOI:10.1016/j.cortex.2012.09.001]
5. Grant JE, Pinto A, Gunnip M, Mancebo MC, Eisen JL, Rasmussen SA. Sexual obsessions and clinical correlates in adults with obsessive-compulsive disorder. Compr Psychiatry. 2006; (5)47: 325-9. [DOI:10.1016/j.comppsych.2006.01.007]
6. Kuelz AK, Hohagen F, Voderholzer U. Neuropsychological performance in obsessive - compulsive disorder: a crtical review. Bio Psychol. 2004; 65(3): 185-236. [DOI:10.1016/j.biopsycho.2003.07.007]
7. Aourizerate B, Guehl D, Cuny E, Rougier A, Biolac B Tignol J. Pathophysiology of obsessive- compulsive disorder: A necessary link between phenomenology, neuropsychology, Imagery and physiology. Prog Neurobiol. 2004; 72(3): 195-221.
8. Gruner P, Pittenger C. Cognitive inflexibility in obsessive- compulsive disorder. Neuroscience. 2017; 345: 243-55. [DOI:10.1016/j.neuroscience.2016.07.030]
9. Evans D, Leckman JF. Origins of obsessive-compulsive disorders: developmental and evolutionary perspective. J Dew psycho. 2006; 72: 321-332.
10. Menzies L, Achard S, Chamberlain SR, Fineberg N, Chen CH, del Campo N, et al. Neurocognitive endophenotypes of obsessive-compulsive disorder. Brain. 2007; 130: 3223-36. [DOI:10.1093/brain/awm205]
11. Chamberlain SR, Blackwell AD, Fineberg NA, Robbins TW, Sahakian BJ.The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. Neurosci & Biobehav Rev. 2005; 29(3): 399-419. [DOI:10.1016/j.neubiorev.2004.11.006]
12. Rao NP, Reddy YJ, Kumar KJ, Kandavel T,Chandrashekar C. Are neuropsychological deficits trait markers in OCD? Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32(6): 1574-9. [DOI:10.1016/j.pnpbp.2008.05.026]
13. Shin N, Lee T, Kim E,Kwon J. Cognitive functioning in obsessive-compulsive disorder: a meta-analysis. Psychol med Sci. 2014; 44(6): 1121-30. [DOI:10.1017/S0033291713001803]
14. Purcell R, Maruff P, Kyrios M, Pantelis C. Cognitive deficits in obsessive-compulsive disorder on tests of frontal-striatal function. Biol Psychiatry. 1998; 43(5): 348-57. [DOI:10.1016/S0006-3223(97)00201-1]
15. Brewin C, Beaton A. Thought suppression, intelligence, and working memory capacity. Behav Res thera. 2002; 40(8): 923-30. [DOI:10.1016/S0005-7967(01)00127-9]
16. Demeter G, CsigoK, Harsanyi A, Nemeth A, Racsmany M. Impaired executive function in obsessive compulsive disorder (OCD). Psychiatr Hung. 2008; 23(2): 85-93.
17. Degeus F, Denys DA, Sitskoormm Westenberg HG. Attention and cognition in patients with obsessive - compulsive disorder. Psychiatry Clin Neurosci. 2007; 67(1): 45-53. [DOI:10.1111/j.1440-1819.2007.01609.x]
18. Park HS, Shin YW, Ha TH, Shin MS, Kim YY, Lee YH, et al. Effect of cognitive training focusing on organizational strategies in patients with obsessive‐compulsive disorder. Psychiatry Clin Neurosci. 2006; 60(6): 718-26. [DOI:10.1111/j.1440-1819.2006.01587.x]
19. Buhlmann U,Decker Sbach T, Engelhard I, Cook LM, Rauch SL, Kathmann N,et al. Cognitive retraining for organizational impairment in obsessive- compulsive disorder. Psychiatry Res. 2006; 144(2-3): 109-16. [DOI:10.1016/j.psychres.2005.10.012]
20. Bannon S, Gonsalvez CJ, Croft RJ, Biyce PM. Executive functions in ibsessive- compulsivedisorder: state or trait deficits? Aust N Z J Psychiatry. 2006; 40(11-12): 1031-8.
21. Clark VP, Coffman BA, Trumbo MC, Gasparovic C. Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a 1H magnetic resonance spectroscopy study. Neurosci Lett. 2011; 500(1): 67-71. [DOI:10.1016/j.neulet.2011.05.244]
22. Alizadeh Goradel J, Pouresmali A, Mowlaie M, Sadeghi Movahed F. The effects of transcranial direct current stimulation on obsession-compulsion, anxiety, and depression of a patient suffering from Obsessive-compulsive Disorder. Practice inClinical Psychology. 2016; 4(2): 75-80. [DOI:10.15412/J.JPCP.06040201]
23. Dinn WM, Aycicegi-Dinn A, Göral F,Karamursel S, Yildirim EA, Hacioglu-Yildirim M, et al. Treatment-resistant obsessive-compulsive disorder: Insights from an open trial of transcranial direct current stimulation (tDCS) to design a RCT. Neurol, Psychiat andBrain Res. 2016; 22(3-4): 146-54.
24. Hogeveen J, Grafman J, Aboseria M, David A, Bikson M, Hauner K. Effects of high-definition and conventional tDCS on response inhibition. Brain Stimul. 2016; 9(5): 720-9. [DOI:10.1016/j.brs.2016.04.015]
25. Narayanaswamy JC, Jose D, Chhabra H, Agarwal SM, Shrinivasa B, Hegde A, et al. Successful application of add-on transcranial direct current stimul (tDCS) for treatment of SSRI resistant OCD. Brain Stimul: 2015; 8(3): 655-7. [DOI:10.1016/j.brs.2014.12.003]
26. Swick D,Jovanovic J. Anterior cingulate cortex and the Stroop task: neuropsychological evidence for topographic specificity. Neuropsychologia. 2002; 40(8): 1240-53. [DOI:10.1016/S0028-3932(01)00226-3]
27. Solís-Ortiz S, Pérez-Luque E, Morado-Crespo L, Gutiérrez-Mu-oz M. Executive functions and selective attention are favored in middle-aged healthy women carriers of the Val/Val genotype of the catechol-o-methyltransferase gene: a behavioral genetic study. Behav Brain Funct. 2010; 6(1): 67. [DOI:10.1186/1744-9081-6-67]
28. Groth-Marnat GE. Neuropsychological assessment in clinical practice: a guide to test interpretation and integration. John Wiley & Sons Inc. 2000; p. 672.
29. Ghadiri F, Jazayeri A, Aashayeri H, Ghazi Tabatabai M.Deficit in Executive Functioning in Patients With Schizo-Obsessive Disorder. Journal of Advances in Cognitive Sciences. 2006; 8(3): 11-24.
30. Hodgson RJ, Rachman S. Obsessional-compulsive complaints. Behav Res Ther. 1977; 15(5): 389-95. [DOI:10.1016/0005-7967(77)90042-0]
31. Emmelkamp P, Beens H. Cognitive therapy with obsessive- compulsive disorder: a comparative evaluation. Behav Res Ther. 1991; 29(3): 293-300. [DOI:10.1016/0005-7967(91)90120-R]
32. Conway M, Csank PA, Holm SL, Blake CK. On assessing individual differences in rumination on sadness. J Pers Assess. 2000; 75(3): 404-25. [DOI:10.1207/S15327752JPA7503_04]
33. Ghasemzadeh H. Cognitive- behavioral model of OCD with emphasis on encountering and emotional processing. 118th seminar on neuro-cognitive psychology. Shohada Medical center. Shahid Beheshti University of Medical Sciences. 2003; 8(2): 25-40.
34. Nitsche MA, Cohen LG, Wassermann EM, Priori A, Lang N, Antal A, et al. Transcranial direct current stimulation: state of the art 2008. Brain Stimul. 2008; 1(3): 206-23. [DOI:10.1016/j.brs.2008.06.004]
35. Fregni F, Boggio PS, Nitsche M, Bermpohl F, Antal A, Feredoes E, et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res. 2005; 166(1): 23-30. [DOI:10.1007/s00221-005-2334-6]
36. Sharifi T, Rabee M. The use of 4th edition of Wechsler exam for kids in recognizing disorders in writing and mathmatics. Journal of Research in Learning Disabilities. 2012; 2(2): 59-75.
37. Altemeier LE, Abbott RD,Berninger VW. Executive functions for reading and writing in typical literacy development and dyslexia. J Clin Exp Neuropsychol. 2008; 30(5): 588-606. [DOI:10.1080/13803390701562818]
38. Zelazo PD. The dimensional changecard sort (dccs): a method of assessing executive function in children. Nat Protoc. 2006; 1(1): 297-301. [DOI:10.1038/nprot.2006.46]
39. Dawson P, Guare R. Executive skills in children and adolescents: a practical guide to assessment and intervention: New York: Guilford Press .2010.
40. André S, Heinrich S, Kayser F, Menzler K, Kesselring J, Khader PH, et al. At-home tDCS of the left dorsolateral prefrontal cortex improves visual short-term memory in mild vascular dementia.J Neurol Sci. 2016; 369: 185-90. [DOI:10.1016/j.jns.2016.07.065]
41. Barkley RA. Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull. 1997; 121(1): 65-94. [DOI:10.1037/0033-2909.121.1.65]
42. Flöel A, Suttorp W, Kohl O, Kürten J, Lohmann H, Breitenstein C, et al. Non-invasive brain stimulation improves object-location learning in the elderly. Neurobiol Aging. 2012; 33(8): 1682-9. [DOI:10.1016/j.neurobiolaging.2011.05.007]
43. Yun GJ, Chun MH, Kim BR. The effects of transcranial direct-current stimulation on cognition in stroke patients. J Stroke. 2015; 17(3): 354-8. [DOI:10.5853/jos.2015.17.3.354]
44. Rosenberg DR, Mirza Y, Russell A, Tang J, Smith JM, Banerjee SP, et al. Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.J Am Acad Child Adolesc Psychiatry. 2004; 43(9): 1146-53. [DOI:10.1097/01.chi.0000132812.44664.2d]
45. Bolton J, Moore GJ, MacMillan S, Stewart CM, Rosenberg DR. Case study: caudate glutamatergic changes with paroxetine persist after medication discontinuation in pediatric OCD. J Am Acad Child Adolesc Psychiatry. 2001; 40(8): 903-6. [DOI:10.1097/00004583-200108000-00011]



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Shahmohammadi Kaleybar M, Bafandeh H, Yousefi R, Rahbaran R. Effect of Transcranial Direct Current Stmulation on the Response Inhibition in Patient with Obsessive Compulsive Disorder. Shefaye Khatam. 2019; 7 (2) :1-12
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Volume 7, Issue 2 (Spring - 2019) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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