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دوره 7 شماره 4 صفحات 106-121 برگشت به فهرست نسخه ها
تاثیر استرس دوران بارداری بر حافظه و یادگیری فرزندان و راهکارهای مقابله با آن
فاطمه عقیقی، محمود سلامی، سید علیرضا طلائی*
مرکز تحقیقات فیزیولوژی، پژوهشکده علوم پایه، دانشگاه علوم پزشکی کاشان، کاشان، ایران ، talaei@kaums.ac.ir
چکیده:   (76 مشاهده)
مقدمه: استرس دوران بارداری عاملی مهم است که بر رشد و عملکرد مغز تأثیر می‌گذارد. مطالعات فراوان نشان داده‌اند که استرس دوران بارداری باعث ایجاد اختلال در حافظه و یادگیری فرزندان می‌گردد. استرس دوران بارداری با فعال کردن بیش از حد محور HPA، فعالیت انتقال‌دهنده‌های عصبی مثل نورآدرنالین، دوپامین و سروتونین را تغییر می‌دهد. علاوه بر این استرس دوران بارداری مقادیر پروتئین‌های مختلف هیپوکامپ درگیر در یادگیری و حافظه و تقویت طولانی‌مدت مانند فاکتور نوروتروفیک مشتق شده از مغز، کلسیم/کالمودولین وابسته به پروتئین کیناز 2، postsynaptic density protein 95 و cAMP response element-binding protein را کاهش می‌دهد. به نظر می‌رسد که ورزش کردن، غنی‌سازی محیط و آنتی‌اکسیدان‌ها می‌توانند نقص یادگیری و حافظه ناشی از استرس دوران بارداری در فرزندان را بهبود بخشند. نتیجه‌گیری: مداخلات برای محافظت از فرزندان در برابر استرس برای حفظ توانایی‌های شناختی آن‌ها بسیار مهم است.
واژه‌های کلیدی: استرس دوران بارداری، یادگیری، حافظه، شکل‌پذیری عصبی
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نوع مطالعه: مروری | موضوع مقاله: تحقیقات پایه در علوم اعصاب
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Aghighi F, Salami M, Talaei A. Effect of Prenatal Stress on Offspring's Learning, Memory and Coping Strategies. Shefaye Khatam. 2019; 7 (4) :106-121
URL: http://shefayekhatam.ir/article-1-2002-fa.html

عقیقی فاطمه، سلامی محمود، طلائی علیرضا. تاثیر استرس دوران بارداری بر حافظه و یادگیری فرزندان و راهکارهای مقابله با آن. مجله علوم اعصاب شفای خاتم. 1398; 7 (4) :106-121

URL: http://shefayekhatam.ir/article-1-2002-fa.html



دوره 7، شماره 4 - ( پاييز 1398 ) برگشت به فهرست نسخه ها
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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