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:: Volume 10, Issue 3 (Summer 2022) ::
Shefaye Khatam 2022, 10(3): 123-129 Back to browse issues page
A Narrative Review of the Role of Orexin in the Epileptogenesis
Taha Ghantabpour , Fariba Karimzadeh *
Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran , Fariba_karimzade@yahoo.com
Abstract:   (962 Views)
Introduction: Epilepsy is a neurological disorder characterized by seizures and affects about 65-70 million people worldwide. Many pathways and molecules are altered in the epilepsy process that can be used as targets in the treatment of epilepsy. Orexin or hypocretin is a type of neurotransmitter that has a role in the epileptogenic process. Conclusion: The orexin system, by acting on the brainstem, modulates the activities of the limbic and neocortical areas, which is involved in epilepsy. In this study, the role of orexin in epilepsy and its potential mechanisms have been reviewed.
Keywords: Orexins, Epilepsy, Neurotransmitter Agents
Full-Text [PDF 426 kb]   (1265 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Neurophysiology
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Ghantabpour T, Karimzadeh F. A Narrative Review of the Role of Orexin in the Epileptogenesis. Shefaye Khatam 2022; 10 (3) :123-129
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Volume 10, Issue 3 (Summer 2022) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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