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The Effectiveness of Photobiomodulation in Mild Cognitive Impairment
Masoud Mehdizadeh , Aliraza Farnam , Behzad Nikzad *
Department of Cognitive Neuroscience, Faculty of Educational Sciences and Psychology, Tabriz University, Tabriz, Iran , blsnikzad@yahoo.com
Abstract:   (61 Views)
Introduction: This study investigated the effectiveness of transcranial photobiomodulation (tPBM) on cognitive functions, including visual working memory, auditory working memory, executive function, and sleep quality in middle-aged patients with mild cognitive impairment (MCI). Materials and Methods: In a quasi-experimental design with pretest-posttest and control group, 20 middle-aged participants with MCI were randomly assigned to the intervention and control groups (10 people in each group). The intervention group was exposed to near-infrared light (810 nm) on the frontal areas for 4 weeks (12 sessions, each session 8 minutes). Cognitive function was tested at baseline, during treatment, and at a one-month follow-up using the N-back test (visual working memory), the Wechsler Digit Span test (auditory working memory), the BRIEF-A questionnaire (executive function), and the Pittsburgh Sleep Quality Index (sleep quality). Results: Results from the repeated measures analysis indicated that the intervention group demonstrated significant improvements in visual working memory, auditory working memory, and executive function scores compared to the control group. However, these improvements declined at the one-month follow-up. Conclusion: tPBM offers a non-invasive and safe approach to enhance cognitive functions in MCI patients, although its effects may not be long-lasting and could require maintenance sessions.
 
Keywords: Cognition, Dementia, Executive Function, Memory, Short-Term, Sleep
Full-Text [PDF 1280 kb]   (10 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Cognitive Neuroscience
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