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:: Volume 3 - The Summer Supplement of Shefaye Khatam 2 - ::
Shefaye Khatam 2015, 3 - The Summer Supplement of Shefaye Khatam 2 -: 31-31 Back to browse issues page
P13: Potassium Channels and Long-Term Potentiation Formation
Ali Jahanbazi Jahan-Abad * , Sedigheh Ghasemi
Shefa Neuroscience Research Center, Khatam Alanbia Hospital Tehran, Iran , a.jahanbazi65@yahoo.com
Abstract:   (3674 Views)

Long-term potentiation (LTP) is a form of activity-dependent plasticity that occurs during learning. Potassium channels are the most diverse group of all ion channels that related to synaptic plasticity. Small-conductance calcium-activated potassium channels (SKs) are found in hippocampal CA1 neurons and by inhibiting of postsynaptic potentials are involved in synaptic transmission impairment. Studies have been shown that blockage of SKs result in increase of LTP so that blocking of these channels increased LTP process and vice versa. Large-conductance calcium-activated potassium channels (BKs) also are found in hippocampal CA1 neurons and by influencing synaptic plasticity play an important role in learning and memory.
 

Keywords: Potassium Channels, Synaptic Plasticity, Long-Term Potentiation
Full-Text [PDF 161 kb]   (1020 Downloads)    
Type of Study: Review --- Open Access, CC-BY-NC | Subject: Basic research in Neuroscience


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Jahanbazi Jahan-Abad A, Ghasemi S. P13: Potassium Channels and Long-Term Potentiation Formation. Shefaye Khatam 2015; 3 (S2) :31-31
URL: http://shefayekhatam.ir/article-1-803-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 3 - The Summer Supplement of Shefaye Khatam 2 - Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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