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:: Volume 4, Issue 2 (Spring - 2016) ::
Shefaye Khatam 2016, 4(2): 87-97 Back to browse issues page
The Role of Stem Cell Therapy in Alzheimer's Disease
Fatemeh Alipour, Maryam Borhani Haghighi *, Hoda Pasand Mojdeh
a. Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran b. Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran , borhanihm@gmail.com
Abstract:   (6388 Views)

Introduction: Alzheimer's disease (AD) is the most ordinary reason of dementia in old population. AD is a permanent and progressive brain disorder that gradually deteriorates memory and speaking skills, and eventually leads to disability to accomplish the effortless skills. In this disease, the brain cells are gradually destroyed and as a result, the patients suffer from amnesia. Definitive treatment for AD has not been found yet and enormous efforts have been made to find novel and effective therapies. The stem cells are undifferentiated cells that have a potential to differentiate into many different cell types. Several studies revealed that neurons and glial cells have successfully been differentiated from various stem cells, such as neural, embryonic, and mesenchymal stem cells. Cell therapy is a potential novel therapeutic strategies for treatment of AD. Conclusion: Successful stem cell therapy in animal models of AD points to a potential therapeutic approach in patients with AD.

Keywords: Alzheimer Disease, Stem Cells, Transplantation, Memory
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Type of Study: Review --- Open Access, CC-BY-NC | Subject: Neurology



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Alipour F, Borhani Haghighi M, Pasand Mojdeh H. The Role of Stem Cell Therapy in Alzheimer's Disease. Shefaye Khatam 2016; 4 (2) :87-97
URL: http://shefayekhatam.ir/article-1-924-en.html


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Volume 4, Issue 2 (Spring - 2016) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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