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دوره 10 شماره 2 صفحات 125-111 برگشت به فهرست نسخه ها
نقش سلول‌های بنیادی مختلف در درمان بیماری‌های تحلیل برندۀ عصبی
فاطمه بهداروند، محمد شاهوردی شهرکی، زهرا سورانی، مصطفی مدرس موسوی، صادق شیریان*
الف. گروه پاتولوژی، دانشکده دامپزشکی، دانشگاه شهرکرد، شهرکرد، ایران. ب. مرکز تحقیقات آسیب‌شناسی مولکولی شیراز، آزمایشگاه آسیب‌شناسی دکتر دانشبد، شیراز، ایران ، Shirian85@gmail.com
چکیده:   (257 مشاهده)
مقدمه: ضایعات سیستم عصبی مرکزی با آثاری گسترده ازجمله تخریب گسترده و مرگ سلول‌های عصبی به دنبال عللی همچون ضربات، خونریزی، ادم و التهاب ایجاد می‌شوند که درنهایت منجر به عدم هماهنگی در حرکات ارادی و اندام‌ها، از دست رفتن حواس یا حتی مرگ می‌شوند. امروزه پژوهشگران تلاش‌های زیادی در جهت یافتن راهکار و شیوۀ درمانی موثر برای درمان بیماری‌های تحلیل برندۀ عصبی کرده‌اند که از این میان سلول‌های بنیادی توانسته‌اند جایگاه ارزشمندی را به دست بیاورند. اگرچه در سال‌های اخیر این محققین گام‌های مهمی در زمینۀ درمان آسیب‌های سیستم عصبی پیموده‌اند ولی درمان قطعی تا به اکنون برای این بیماری‌ها یافت نشده است. در این مطالعه نقش سلول‌های بنیادی در درمان بیماری‌های تحلیل برندۀ عصبی مورد بررسی قرارگرفته است. در این مقالۀ مروری با بررسی تحقیقات انجام‌ شده، در مورد انواع سلول‌های بنیادی مختلف، مزایا و معایب هرکدام در درمان بیماری‌های تحلیل برندۀ عصبی و نحوۀ عملکرد آن‌ها مورد بحث قرارگرفته است. نتیجه‌گیری: در حال حاضر انواع مختلف سلول‌های بنیادی با قابلیت‌های بالا در رفع مشکلات سیستم عصبی می‌توانند امید به استفاده از روش‌های درمانی جدید برای درمان بیماری‌های تحلیل برندۀ عصبی را به شکل چشم‌گیری افزایش دهند. هزینۀ بالای درمان و عوارض جانبی احتمالی، چالش‌های اصلی در درمان مبتنی بر سلول‌های بنیادی است و تحقیقات بیشتری برای بهبود کارایی سلول‌های بنیادی در محیط‌ های بالینی موردنیاز است.
 
واژه‌های کلیدی: بیماری‌های تحلیل برندۀ عصبی، درمان، سلول‌های بنیادی
متن کامل [PDF 649 kb]   (27 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: تحقیقات پایه در علوم اعصاب
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Behdarvand F, Shahverdi Shahraki M, Sourani Z, Modarres Mousavi M, Shirian S. Roles of different types of stem cells in treating neurodegenerative disease. Shefaye Khatam. 2022; 10 (2) :111-125
URL: http://shefayekhatam.ir/article-1-2319-fa.html

بهداروند فاطمه، شاهوردی شهرکی محمد، سورانی زهرا، مدرس موسوی مصطفی، شیریان صادق. نقش سلول‌های بنیادی مختلف در درمان بیماری‌های تحلیل برندۀ عصبی. مجله علوم اعصاب شفای خاتم. 1401; 10 (2) :125-111

URL: http://shefayekhatam.ir/article-1-2319-fa.html



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