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:: Volume 13, Issue 1 (Winter 2024) ::
Shefaye Khatam 2024, 13(1): 16-26 Back to browse issues page
Investigating the Effectiveness of Transcranial Direct Current Stimulation on Enhancing the Attention Network in Adults with Amblyopia
Mohammad Maeiyat , Soomaayeh Heysieattalab * , Khalil Esmaeilpour
Department of Cognitive Neuroscience, Faculty of Educational and Psychology, University of Tabriz, Tabriz, Iran , heysieattalab@gmail.com
Abstract:   (439 Views)
Introduction: Amblyopia is a visual impairment, often unilateral, caused by a developmental disorder that can be associated with cognitive deficits, including attention disorders. This study aimed to investigate the effectiveness of transcranial direct current stimulation (tDCS) in improving the attention network in adults with amblyopia. Materials and Methods: This quasi-experimental study employed a pretest-posttest design with a sham-controlled group. The study population included adults aged 20 to 35 with amblyopia who were referred to optometry clinics in Meshginshahr in 1402. Using purposive sampling, 30 individuals were selected and randomly assigned to either the tDCS group (n = 15) or the sham group (n = 15). The experimental group received 10 sessions of 20-minute tDCS applied to the dorsolateral prefrontal cortex (three sessions per week), while the sham group received placebo stimulation. To assess attentional function, the Attention Network Test was administered before and immediately after the intervention. Results: The findings demonstrated that tDCS significantly improved the attention network in adults with amblyopia, indicating its effectiveness in enhancing attentional processing. Conclusion: Our results suggest that tDCS, by directly modulating the attention network, may serve as an adjunct therapy to enhance the effectiveness of amblyopia treatment in adults.
 
Keywords: Vision, Ocular, Prefrontal Cortex, Optometry
Full-Text [PDF 1156 kb]   (189 Downloads)    
Type of Study: Research --- Open Access, CC-BY-NC | Subject: Cognitive Neuroscience
References
1. Birch EE. Amblyopia and binocular vision. Progress in Retinal and Eye Research. 2013; 33: 67-84. [DOI:10.1016/j.preteyeres.2012.11.001]
2. Wong AM. New concepts concerning the neural mechanisms of amblyopia and their clinical implications. Canadian Journal of Ophthalmology. 2012; 47(5): 399-409. [DOI:10.1016/j.jcjo.2012.05.002]
3. Carrasco M. How visual spatial attention alters perception. Cogn Process. 2018; 19(Suppl 1): 77-88. [DOI:10.1007/s10339-018-0883-4]
4. Rizzolatti G, Riggio L, Dascola I, Umiltá C. Reorienting attention across the horizontal and vertical meridians: evidence in favor of a premotor theory of attention. Neuropsychologia. 1987; 25(1a): 31-40. [DOI:10.1016/0028-3932(87)90041-8]
5. Atkinson J, Braddick O. Visual attention in the first years: typical development and developmental disorders. Developmental Medicine & Child Neurology. 2012; 54(7): 589-95. [DOI:10.1111/j.1469-8749.2012.04294.x]
6. Popple AV, Levi DM. The attentional blink in amblyopia. Journal of Visualized Medicine. 2008; 8(13): 12.1-9. [DOI:10.1167/8.13.12]
7. Tripathy SP, Levi DM. On the effective number of tracked trajectories in amblyopic human vision. Journal of Visualized Medicine. 2008; 8(4): 8.1-22. [DOI:10.1167/8.4.8]
8. Sharma V, Levi DM, Klein SA. Undercounting features and missing features: evidence for a high-level deficit in strabismic amblyopia. Nature Neuroscience 2000; 3(5): 496-501. [DOI:10.1038/74872]
9. Farzin F, Norcia AM. Impaired visual decision-making in individuals with amblyopia. Journal of Visualized Medicine. 2011; 11(14). [DOI:10.1167/11.14.6]
10. Ho CS, Paul PS, Asirvatham A, Cavanagh P, Cline R, Giaschi DE. Abnormal spatial selection and tracking in children with amblyopia. Vision Research. 2006; 46(19): 3274-83. [DOI:10.1016/j.visres.2006.03.029]
11. Black AA, Wood JM, Hoang S, Thomas E, Webber AL. Impact of Amblyopia on Visual Attention and Visual Search in Children. Investigative Ophthalmology & Visual Science. 2021; 62(4): 15. [DOI:10.1167/iovs.62.4.15]
12. Chung ST, Kumar G, Li RW, Levi DM. Characteristics of fixational eye movements in amblyopia: Limitations on fixation stability and acuity? Vision Research. 2015; 114: 87-99. [DOI:10.1016/j.visres.2015.01.016]
13. González EG, Wong AM, Niechwiej-Szwedo E, Tarita-Nistor L, Steinbach MJ. Eye position stability in amblyopia and in normal binocular vision. Investigative Ophthalmology & Visual Science. 2012; 53(9); 5386-94. [DOI:10.1167/iovs.12-9941]
14. McKee SP, Levi DM, Schor CM, Movshon JA. Saccadic latency in amblyopia. Journal of Visualized Medicine. 2016; 16(5): 3. [DOI:10.1167/16.5.3]
15. Kowler E, Anderson E, Dosher B, Blaser E. The role of attention in the programming of saccades. Vision Research. 1995; 13(5); 1897-916. [DOI:10.1016/0042-6989(94)00279-U]
16. Carpenter RHS. Movements of the Eyes: Pion; 1988.
17. Rolfs M, Laubrock J, Kliegl R. Shortening and prolongation of saccade latencies following microsaccades. Experimental Brain Research 2006; 169(3): 369-76. [DOI:10.1007/s00221-005-0148-1]
18. Verghese P, McKee SP, Levi DM. Attention deficits in amblyopia. Current Opinion in Psychology. 2019; 29: 199-204. [DOI:10.1016/j.copsyc.2019.03.011]
19. Posner MI. Orienting of attention. Quarterly Journal of Experimental Psychology. 1980; 32(1): 3-25. [DOI:10.1080/00335558008248231]
20. McConaghy JR, McGuirk R. Amblyopia: Detection and Treatment. American Family Physician. 2019; 100(12): 745-50.
21. Maconachie GD, Gottlob I. The challenges of amblyopia treatment. Biomedical Journal 2015; 38(6): 510-6. [DOI:10.1016/j.bj.2015.06.001]
22. Maya-Vetencourt JF, Baroncelli L, Viegi A, Tiraboschi E, Castren E, Cattaneo A, et al. IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels. Neural Plasticity. 2012; 2012: 250421. [DOI:10.1155/2012/250421]
23. Black JM, Hess RF, Cooperstock JR, To L, Thompson B. The measurement and treatment of suppression in amblyopia. Journal of Visualized Experiments. 2012(70): e3927. [DOI:10.3791/3927]
24. Levi DM, Li RW. Perceptual learning as a potential treatment for amblyopia: a mini-review. Vision Research. 2009; 49(21): 2535-49. [DOI:10.1016/j.visres.2009.02.010]
25. Gambacorta C, Nahum M, Vedamurthy I, Bayliss J, Jordan J, Bavelier D, et al. An action video game for the treatment of amblyopia in children: A feasibility study. Vision Research. 2018; 148: 1-14. [DOI:10.1016/j.visres.2018.04.005]
26. Kelly KR, Jost RM, Wang YZ, Dao L, Beauchamp CL, Leffler JN, et al. Improved Binocular Outcomes Following Binocular Treatment for Childhood Amblyopia. Investigative Ophthalmology & Visual Science. 2018; 59(3): 1221-8. [DOI:10.1167/iovs.17-23235]
27. Webber AL, Wood JM, Thompson B. Fine Motor Skills of Children With Amblyopia Improve Following Binocular Treatment. Investigative Ophthalmology & Visual Science. 2016; 57(11): 4713-20. [DOI:10.1167/iovs.16-19797]
28. Tsirlin I, Colpa L, Goltz HC, Wong AM. Behavioral Training as New Treatment for Adult Amblyopia: A Meta-Analysis and Systematic Review. Investigative Ophthalmology & Visual Science. 2015; 56(6): 4061-75. [DOI:10.1167/iovs.15-16583]
29. Amouzadeh F, Moradi H, Gharayagh zandi h, Rostani R, Moghadamzadeh A. Impact of Video Game Minecraft on the Sustained Visual Attention of Athlete's Student With Hyperactivity/Attention Deficit Disorder. The Neuroscience Journal of Shefaye Khatam. 2023; 11(3): 36-46. [DOI:10.61186/shefa.11.3.36]
30. Spiegel DP, Hansen BC, Byblow WD, Thompson B. Anodal transcranial direct current stimulation reduces psychophysically measured surround suppression in the human visual cortex. PLoS One. 2012; 7(5): e36220. [DOI:10.1371/journal.pone.0036220]
31. Thompson B, Mansouri B, Koski L, Hess RF. Brain plasticity in the adult: modulation of function in amblyopia with rTMS. Current Biology. 2008; 18(14): 1067-71. [DOI:10.1016/j.cub.2008.06.052]
32. Thompson B, Mansouri B, Koski L, Hess RF. From motor cortex to visual cortex: the application of noninvasive brain stimulation to amblyopia. Developmental Psychobiology. 2012; 54(3): 263-73. [DOI:10.1002/dev.20509]
33. Spiegel DP, Byblow WD, Hess RF, Thompson B. Anodal transcranial direct current stimulation transiently improves contrast sensitivity and normalizes visual cortex activation in individuals with amblyopia. Neurorehabilitation & Neural Repair 2013; 27(8): 760-9. [DOI:10.1177/1545968313491006]
34. Benninger DH, Lomarev M, Lopez G, Pal N, Luckenbaugh DA, Hallett M. Transcranial direct current stimulation for the treatment of focal hand dystonia. Movement Disorders. 2011; 26(9): 1698-702. [DOI:10.1002/mds.23691]
35. Castillo-Astorga R, Del Valle-Batalla L, Mariman JJ, Plaza-Rosales I, de los Angeles Juricic M, Maldonado PE, et al. Combined therapy of bilateral transcranial direct current stimulation and ocular occlusion improves visual function in adults with amblyopia, a randomized pilot study. Frontiers in Human Neuroscience. 2023; 17. [DOI:10.3389/fnhum.2023.1056432]
36. Bocci T, Nasini F, Caleo M, Restani L, Barloscio D, Ardolino G, et al. Unilateral Application of Cathodal tDCS Reduces Transcallosal Inhibition and Improves Visual Acuity in Amblyopic Patients. Frontiers in Behavioral Neuroscience. 2018; 12: 109. [DOI:10.3389/fnbeh.2018.00109]
37. Ding Z, Li J, Spiegel DP, Chen Z, Chan L, Luo G, et al. The effect of transcranial direct current stimulation on contrast sensitivity and visual evoked potential amplitude in adults with amblyopia. Scientific Reports 2016; 6: 80-92. [DOI:10.1038/srep19280]
38. Sengpiel F, Jirmann KU, Vorobyov V, Eysel UT. Strabismic suppression is mediated by inhibitory interactions in the primary visual cortex. cerebral cortex. 2006; 16(12): 1750-8. [DOI:10.1093/cercor/bhj110]
39. Esmaili Jami A, Khalilzadeh MA, Ghoshuni M, Khalilzadeh MM. Estimation of Attention Indices in IVA Tests Using Optical Flow in ERP Brain Maps. The Neuroscience Journal of Shefaye Khatam. 2022; 11(1): 46-56. [DOI:10.52547/shefa.11.1.46]
40. Shamsi Holasu M, Tabatabaei M, Azmodeh M. The Effectiveness of Transcranial Direct Current Stimulation on the Executive Functions of Children with Autism Spectrum Disorders. The Neuroscience Journal of Shefaye Khatam. 2023; 11(2): 20-31. [DOI:10.61186/shefa.11.2.20]
41. Mahdavi A, Ahmadi F, Haj Abbas Tabrizi E, Gharaian H, Rigi Koote B, Imaninasab V, et al. Transcranial Electrical Stimulation (tES): History, Theoretical Foundations and Applications. The Neuroscience Journal of Shefaye Khatam. 2022; 11(1): 69-104. [DOI:10.52547/shefa.11.1.69]
42. Faul F, Erdfelder E, Lang AG, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods. 2007; 39(2): 175-91. [DOI:10.3758/BF03193146]
43. Fan J, McCandliss BD, Sommer T, Raz A, Posner MI. Testing the efficiency and independence of attentional networks. Journal of Cognitive Neuroscience. 2002; 14(3): 340-7. [DOI:10.1162/089892902317361886]
44. Hosseini Z, Talepasand S. Psychometric properties of the attention network test in Iranian children and adults. Institute for Cognitive Science Studies. 2022; 24(1): 84-97.
45. Castaño-Castaño S, Feijoo-Cuaresma M, Paredes-Pacheco J, Morales-Navas M, Ruiz-Guijarro JA, Sanchez-Santed F, et al. tDCS recovers depth perception in adult amblyopic rats and reorganizes visual cortex activity. Behavioural Brain Research. 2019; 370: 111941. [DOI:10.1016/j.bbr.2019.111941]
46. Ding K, Liu Y, Yan X, Lin X, Jiang T. Altered functional connectivity of the primary visual cortex in subjects with amblyopia. Neural Plasticity. 2013; 2013: 612086. [DOI:10.1155/2013/612086]
47. Levi DM, Knill DC, Bavelier D. Stereopsis and amblyopia: A mini-review. Vision Research. 2015; 114: 17-30. [DOI:10.1016/j.visres.2015.01.002]
48. Kiorpes L, Kiper DC, O'Keefe LP, Cavanaugh JR, Movshon JA. Neuronal correlates of amblyopia in the visual cortex of macaque monkeys with experimental strabismus and anisometropia. Journal of Neuroscience. 1998; 18(16): 6411-24. [DOI:10.1523/JNEUROSCI.18-16-06411.1998]
49. Li X, Dumoulin SO, Mansouri B, Hess RF. Cortical deficits in human amblyopia: their regional distribution and their relationship to the contrast detection deficit. Investigative Ophthalmology & Visual Science. 2007; 48(4): 1575-91. [DOI:10.1167/iovs.06-1021]
50. Vidyasagar TR. Gating of neuronal responses in macaque primary visual cortex by an attentional spotlight. Neuroreport. 1998; 9(9): 1947-52. [DOI:10.1097/00001756-199806220-00006]
51. Ooi TL, He ZJ. Binocular rivalry and visual awareness: The role of attention. Perception. 1999; 28(5): 551-74. [DOI:10.1068/p2923]
52. Gutnisky DA, Hansen BJ, Iliescu BF, Dragoi V. Attention alters visual plasticity during exposure-based learning. Current Biology. 2009; 19(7): 555-60. [DOI:10.1016/j.cub.2009.01.063]
53. Hou C, Kim YJ, Lai XJ, Verghese P. Degraded attentional modulation of cortical neural populations in strabismic amblyopia. Journal of Visualized Medicine. 2016; 16(3): 16. [DOI:10.1167/16.3.16]
54. Wu S, Cheng CK, Feng J, D'Angelo L, Alain C, Spence I. Playing a first-person shooter video game induces neuroplastic change. Journal of Cognitive Neuroscience. 2012; 24(6): 1286-93. [DOI:10.1162/jocn_a_00192]

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Maeiyat M, Heysieattalab S, Esmaeilpour K. Investigating the Effectiveness of Transcranial Direct Current Stimulation on Enhancing the Attention Network in Adults with Amblyopia. Shefaye Khatam 2024; 13 (1) :16-26
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Volume 13, Issue 1 (Winter 2024) Back to browse issues page
مجله علوم اعصاب شفای خاتم The Neuroscience Journal of Shefaye Khatam
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