1. Vassoler FM, Wimmer ME. Consequences of Parental Opioid Exposure on Neurophysiology, Behavior, and Health in the Next Generations. Cold Spring Harb Perspect Med. 2021; 11(10). [DOI:10.1101/cshperspect.a040436]

2. Wen X, Lawal OD, Belviso N, Matson KL, Wang S, Quilliam BJ, et al. Association Between Prenatal Opioid Exposure and Neurodevelopmental Outcomes in Early Childhood: A Retrospective Cohort Study. Drug Saf. 2021; 44(8): 863-75. [DOI:10.1007/s40264-021-01080-0]

3. Akbarabadi A, Sadat-Shirazi MS, Kabbaj M, Nouri Zadeh-Tehrani S, Khalifeh S, Pirri F, et al. Effects of Morphine and Maternal Care on Behaviors and Protein Expression of Male Offspring. Neuroscience. 2021; 466: 58-76. [DOI:10.1016/j.neuroscience.2021.04.011]

4. Soltani H, Sadat-Shirazi MS, Pakpour B, Ashabi G, Zarrindast MR. Toxic effect of calcium/calmodulin kinase II on anxiety behavior, neuronal firing and plasticity in the male offspring of morphine-abstinent rats. Behav Brain Res. 2020; 395: 112877. [DOI:10.1016/j.bbr.2020.112877]

5. Sarkaki A, Assaei R, Motamedi F, Badavi M, Pajouhi N. Effect of parental morphine addiction on hippocampal long-term potentiation in rats offspring. Behav Brain Res. 2008; 186(1): 72-7. [DOI:10.1016/j.bbr.2007.07.041]

6. Ashabi G, Matloob M, Monfared Neirizi N, Behrouzi M, Safarzadeh M, Rajabpoor Dehdashti A, et al. Activation of D1-like dopamine receptors is involved in the impairment of spatial memory in the offspring of morphine-abstinent rats. Neurosci Res. 2020; 158: 37-46. [DOI:10.1016/j.neures.2019.10.003]

7. Schindler CJ, Slamberova R, Vathy I. Prenatal morphine exposure decreases susceptibility of adult male rat offspring to bicuculline seizures. Brain Res. 2001; 922(2): 305-9. [DOI:10.1016/S0006-8993(01)03183-3]

8. Wu PL, Suen JL, Yang CH, Kuo KC, Yang YSH, Yang SN. Enhanced H3K4 Trimethylation in TNF-alpha Promoter Gene Locus with Cell Apoptosis in the Ventral-Medial Striatum following Opioid Withdrawal of Neonatal Rat Offspring from Morphine-Addicted Mothers. Mediators Inflamm. 2021; 2021: 9828. [DOI:10.1155/2021/9828995]

9. Yang SN, Huang LT, Wang CL, Chen WF, Yang CH, Lin SZ, et al. Prenatal administration of morphine decreases CREBSerine-133 phosphorylation and synaptic plasticity range mediated by glutamatergic transmission in the hippocampal CA1 area of cognitive-deficient rat offspring. Hippocampus. 2003;13(8): 915-21. [DOI:10.1002/hipo.10137]

10. Gilardi F, Augsburger M, Thomas A. Will Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations? Front Pharmacol. 2018; 9: 702. [DOI:10.3389/fphar.2018.00702]

11. Dunn KE, Bird HE, Bergeria CL, Ware OD, Strain EC, Huhn AS. Operational definition of precipitated opioid withdrawal. Front Psychiatry. 2023; 14: 1141980. [DOI:10.3389/fpsyt.2023.1141980]

12. Sadat-Shirazi MS, Monfared Neirizi N, Matloob M, Safarzadeh M, Behrouzi M, Rajabpoor Dehdashti A, et al. Possible involvement of nucleus accumbens D1-like dopamine receptors in the morphine-induced condition place preference in the offspring of morphine abstinent rats. Life Sci. 2019; 233: 116712. [DOI:10.1016/j.lfs.2019.116712]

13. Barnes CA. Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol. 1979; 93(1): 74-104. [DOI:10.1037/h0077579]

14. Alipour V, Shojaei A, Rezaei M, Mirnajafi-Zadeh J, Azizi H. Intergenerational consequences of adolescent morphine exposure on learning and memory. Neurosci Lett. 2023; 808: 137303. [DOI:10.1016/j.neulet.2023.137303]

15. Saberi Moghadam A, Sepehri G, Sheibani V, Haghpanah T, Divsalar K, Hajzadeh MA, et al. The Effect of Opium Dependency of Parent (s) on Offspring's Spatial Learning & Memory in Adult Male Rats. Iran J Basic Med Sci. 2013; 16(5): 694-9.

16. Ferrante JR, Blendy JA. Advances in animal models of prenatal opioid exposure. Trends Neurosci. 2024; 47(5): 367-82. [DOI:10.1016/j.tins.2024.03.005]

17. Tolomeo S, Davey F, Steele JD, Baldacchino AM. Effects of Opioid Dependence on Visuospatial Memory and Its Associations With Depression and Anxiety. Front Psychiatry. 2019; 10: 743. [DOI:10.3389/fpsyt.2019.00743]

18. Radecki DT, Brown LM, Martinez J, Teyler TJ. BDNF protects against stress-induced impairments in spatial learning and memory and LTP. Hippocampus. 2005; 15(2): 246-53. [DOI:10.1002/hipo.20048]

19. Rohbani K, Sabzevari S, Sadat-Shirazi MS, Nouri Zadeh-Tehrani S, Ashabi G, Khalifeh S, et al. Parental morphine exposure affects repetitive grooming actions and marble burying behavior in the offspring: Potential relevance for obsessive-compulsive like behavior. Eur J Pharmacol. 2019; 865: 172757. [DOI:10.1016/j.ejphar.2019.172757]

20. Ahmadian-Moghadam H, Sadat-Shirazi MS, Seifi F, Niknamfar S, Akbarabadi A, Toolee H, et al. Transgenerational influence of parental morphine exposure on pain perception, anxiety-like behavior and passive avoidance memory among male and female offspring of Wistar rats. EXCLI J. 2019; 18: 1019-36.

21. Nyberg H, Bogen IL, Nygaard E, Achterberg M, Andersen JM. Maternal exposure to buprenorphine, but not methadone, during pregnancy reduces social play behavior across two generations of offspring. Psychopharmacology (Berl). 2025; 242(3): 663-80. [DOI:10.1007/s00213-024-06718-2]