Worldwide, more than 185,000 children under 18 years die from road traffic accidents annually (each four minutes a child death occurred due to road crashes); with most casualties from developing countries. 95% of road traffic fatalities among children occur in developing countries. Many more children are injured, often severely, and suffering from different disabilities. Road accidents cause extensive psychological disorders and grief, and occasionally economic hardship for families. Furthermore, traffic accidents cost societies precious resources, diverting these from other health as well as development challenges. Mandating and enforcing child restraint laws for all private vehicles, putting in place internationally recognized manufacturing standards for child road safety, improving children’s ability to see and be seen, adapting vehicle design for children, providing appropriate care for injured children, etc., are important points in enhancement of children road safety Road crash death, injury, and disability are preventable. This is crucial for each country to address these points in order to save the lives of thousands of children and protect their nations countless resources.