Introduction: Patient centeredness care is the extent of interaction between physicians and patient that requires vision and understanding of the patient as a person in addition to the illness. Since the aim of establishing quality management systems is accountability, transparency, and justice, this study was aimed to assess the impact of quality management system on patient centeredness. Materials and Methods: The study population included all patients at infertility care center with a sample size of 384 cases obtained from Morgan method. The confirmed patient centeredness questionnaire-infertility with 45 questions in 8 aspect, access (2 questions), information and explanations (12 questions), communication skills of employees (6 questions), participation in treatment (3 questions), respect for the values and needs (6 questions), duration of treatment (6 questions), qualified staff (6 questions), and organization of care (4 questions) was measured. After the establishment of quality management system, the same questionnaire was applied again. Results: The results showed that there is no significance difference at any dimension of patient centeredness before and after establishment of quality system management. Conclusion: The quality management system is not effective on patient-centered treatment and should be used alongside other quality models.