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Volume 12, Issue 3 (Summer 2024) |
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Review of Functional Mechanisms of Linalool in the Central Nervous System
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Zahra Sarhadi   , Tahereh Ghadiri , Negin Masoomabadi * |
| Department of Neuroscience and Cognition, Faculty of Modern Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran , masoomabadin@tbzmed.ac.ir |
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Abstract: (846 Views) |
Introduction: Linalool is one of the active monoterpene alcohols found in many plants, such as lavender, rosemary, and jasmine. This compound has anti-inflammatory, antibacterial, and antimicrobial properties and is a popular aromatic compound in cosmetics and health industries. Linalool has two optical isomers, R and S, with different aroma profiles. Recently, many studies have been conducted on the effects of linalool on the central nervous system, which has shown that this compound can positively affect brain function. Numerous studies have demonstrated that linalool possesses neuroprotective, anti-inflammatory, and antioxidant properties. Furthermore, it demonstrates sedative, anti-anxiety, antidepressant, anticonvulsant, analgesic, and anti-Alzheimer's effects. Conclusion: Linalool holds promise as a natural compound for enhancing cognitive performance and supporting brain health. However, further research is needed to clarify its precise mechanisms of action and assess its long-term effects. This review article provides a comprehensive overview of linalool's impact on the brain, highlighting its antioxidant, anti-apoptotic, and anti-inflammatory properties in various neurological disorders.
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| Keywords: Neuroprotective Agents, Antioxidants, Inflammation, Anti-Anxiety Agents, Alzheimer Disease |
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Full-Text [PDF 893 kb]
(290 Downloads)
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Type of Study: Review --- Open Access, CC-BY-NC |
Subject:
Neuropharmacology
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